Emerging Infectious Disease ISSN: 1080-6059

A Pilot Study of Host Genetic Variants Associated with Influenza-associated Deaths among Children and Young Adults1

Jill M. Ferdinands

, Amy M. Denison, Nicole F. Dowling, Heather A. Jost, Marta L. Gwinn, Lindy Liu, Sherif R. Zaki, and David K. Shay

Author affiliations: Centers for Disease Control and Prevention, Atlanta, Georgia, USA

Figure 2

Frequency and 95% confidence intervals for fatal influenza cases (n = 105) compared with the NHANES reference group for pooled structural genotypes (AA/AO/OO) of MBL2 and categorization of MBL production on the basis of genotype (low/intermediate/high). Frequencies did not differ significantly between cases and the reference group. MBL, mannose-binding lectin; NHANES, National Health and Nutrition Examination Survey; MBL2, mannose-binding lectin gene. Error bars represent confidence intervals.

Figure 2. Frequency and 95% confidence intervals for fatal influenza cases (n = 105) compared with the NHANES reference group for pooled structural genotypes (AA/AO/OO) of MBL2 and categorization of MBL production on the basis of genotype (low/intermediate/high). Frequencies did not differ significantly between cases and the reference group. MBL, mannose-binding lectin; NHANES, National Health and Nutrition Examination Survey; MBL2, mannose-binding lectin gene. Error bars represent confidence intervals.

Main Article

¹Portions of this study were presented at the Options for the Control of Influenza VII meeting, September 3–7, 2010, Hong Kong.

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