Volume 17, Number 5—May 2011
Research
Evolution of New Genotype of West Nile Virus in North America
Allison R. McMullen, Fiona J. May, Li Li, Hilda Guzman, Rudy Bueno, James A. Dennett, Robert B. Tesh, and Alan D.T. Barrett
Table A2
Genotype nucleotide changes in SW/WN03 isolate of West Nile virus, Upper Texas Gulf Coast, USA*
| Strain |
State |
Year |
Group |
E | NS1 | NS3 | NS4A | NS4B | NS5 | 3′ UTR | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1320 |
1974 |
3399 |
6238 |
6721† |
6765 |
6936 |
7269 |
8550 |
8621‡ |
9264 |
9660 |
10062 |
||||||||||
| NY99 | NY | 1999 | A | C | U | C | G | U | U | U | C | A | U | C | U | |||||||
| CO 2003–2 | CO | 2003 | 1 | · | · | · | U§ | A | · | · | C | · | · | C | · | · | ||||||
| HM488201 | NY | 2007 | · | · | · | U | A | · | · | C | · | · | C | · | · | |||||||
| M12214 | TX | 2005 | 2 | · | · | · | U | A | · | · | · | U | · | C | U | · | ||||||
| BSL2–05 | SD | 2005 | · | · | · | U | A | · | · | · | U | · | C | U | · | |||||||
| TX 6647 | TX | 2007 | · | · | · | U | A | · | · | · | U | · | C | U | · | |||||||
| TX 7558 | TX | 2008 | · | · | · | U | A | · | · | · | U | · | C | U | · | |||||||
| HM488191 | IL | 2004 | 3 | G | · | · | U | A | · | · | · | U | G | C | U | · | ||||||
| 04–237NM | NM | 2004 | G | · | · | U | A | · | · | · | U | G | C | U | · | |||||||
| 04–236NM | NM | 2004 | G | · | · | U | A | · | · | · | U | G | C | U | · | |||||||
| HM488198 | IL | 2005 | G | · | · | U | A | · | · | · | U | G | C | U | · | |||||||
| HM756675 | NY | 2005 | G | · | · | U | A | · | · | · | U | G | C | U | · | |||||||
| HM488239 | NY | 2008 | G | · | · | U | A | · | · | · | U | G | C | U | · | |||||||
| TVP9117 | MEX | 2003 | 4 | G | · | · | · | A | · | · | · | U | G | · | U | · | ||||||
| TVP9223 | MEX | 2003 | G | · | · | U | A | · | · | · | U | G | · | U | · | |||||||
| TVP9115 | MEX | 2003 | G | · | · | U | A | · | · | · | U | G | · | U | · | |||||||
| TVP9222 | MEX | 2003 | G | · | · | U | A | · | · | · | U | G | · | U | · | |||||||
| TVP9218 | MEX | 2003 | G | · | · | U | A | · | · | · | U | G | · | U | · | |||||||
| TVP9220 | MEX | 2003 | G | · | · | U | A | · | · | · | U | G | · | U | · | |||||||
| TVP9219 | MEX | 2003 | G | · | · | U | A | · | · | · | U | G | · | U | · | |||||||
| TVP9221 | MEX | 2003 | G | · | · | U | A | · | · | · | U | G | · | U | · | |||||||
| AZ-03–1623 | AZ | 2003 | 5 | G | U | C | U | A | C | C | C | U | G | C | U | C | ||||||
| AZ-03 03–1799 | AZ | 2003 | G | U | C | U | A | C | C | C | U | G | C | U | C | |||||||
| AZ-03–1681 | AZ | 2003 | G | U | C | U | A | C | C | C | U | G | C | U | C | |||||||
| BSL5–04 | AZ | 2004 | G | U | C | U | A | C | C | C | U | G | C | U | C | |||||||
| 04–252AZ | AZ | 2004 | G | U | C | U | A | C | C | C | U | G | C | U | C | |||||||
| 04–251AZ | AZ | 2004 | G | U | C | U | A | C | C | C | U | G | C | U | C | |||||||
| AZ2004 | AZ | 2004 | G | U | C | U | A | C | C | C | U | G | C | U | C | |||||||
| 04–216CO | CO | 2004 | G | U | C | U | A | C | C | C | U | G | C | U | C | |||||||
| 04–219CO | CO | 2004 | G | U | C | U | A | C | C | C | U | G | C | U | C | |||||||
| BSL13–05 | AZ | 2005 | G | U | C | U | A | C | C | C | U | G | C | U | C | |||||||
| 142WG-AZ05PI | AZ | 2005 | G | U | C | U | A | C | C | C | U | G | C | U | C | |||||||
| 132WG-CA05LA | CA | 2005 | G | U | C | U | A | C | C | C | U | G | C | · | C | |||||||
| HM756677 | NM | 2005 | G | U | C | U | A | C | C | C | U | G | C | U | C | |||||||
| 009WG-NM05LC | NM | 2005 | G | U | C | U | A | C | C | C | U | G | C | U | C | |||||||
| GCTX1–2005 | TX | 2005 | G | U | C | U | A | C | C | C | U | G | · | · | C | |||||||
| 007WG-TX05EP | TX | 2005 | G | U | C | U | A | C | C | C | U | G | C | U | C | |||||||
| 144WG-AZ06PI | AZ | 2006 | G | U | C | U | A | C | · | C | U | G | C | U | C | |||||||
| 011WG-TX06EP | TX | 2006 | G | U | C | U | A | C | C | C | U | G | C | U | C | |||||||
| 194WG-CA07LA | CA | 2007 | G | U | C | U | A | C | C | C | U | G | C | U | C | |||||||
| 013WG-TX07EP | TX | 2007 | G | U | C | U | A | C | C | C | U | G | C | U | C | |||||||
| M19433 | TX | 2007 | G | U | C | U | A | C | C | C | U | G | C | U | C | |||||||
| JPW080814–01 | CA | 2008 | G | U | C | U | A | C | C | C | U | G | C | U | C | |||||||
*E, envelope; NS, nonstructural; UTR, untranslated region; NY, New York; CO, Colorado; TX, Texas; SD, South Dakota; IL, Illinois, NM, New Mexico; MEX, Mexico, AZ, Arizona; CA, California. Dots indicate no change from NY99 isolate. Isolates in boldface were sequenced in this study.
†NS4A-A85T.
‡NS5-K314R.
§Nucleotide changes compared with NY99 isolate.
