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Volume 17, Number 6—June 2011


Multiple Introductions of Multidrug-Resistant Tuberculosis into Households, Lima, Peru

Ted CohenComments to Author , Megan Murray, Ibrahim Abubakar, Zibiao Zhang, Alexander Sloutsky, Fernando Arteaga, Katiuska Chalco, Molly F. Franke, and Mercedes C. Becerra
Author affiliations: Author affiliations: Brigham and Women’s Hospital, Boston, Massachusetts, USA (T. Cohen, M. Murray, Z. Zhang, M.C. Becerra); Harvard School of Public Health, Boston (T. Cohen, M. Murray); University of East Anglia, Norwich, UK (I. Abubakar); Health Protection Agency Centre for Infections, London, UK (I. Abubakar); University of Massachusetts Medical School, Boston (A. Sloutsky); Partners In Health, Boston and Lima, Peru (F. Arteaga, K. Chalco, M.F. Franke, M.C. Becerra); and Harvard Medical School, Boston (M.F. Franke, M.C. Becerra)

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Table 2

Association between household factors and repeated introduction of MDR TB, Lima, Peru, 1996–2004*

Factor Introduction, n = 10† No introduction, n = 91 p value
No. persons 7.5 (6–8) 8 (7–11) 0.18
Persons per bedroom 2.6 (1.7–2.7) 2.4 (1.75–5) 0.43
Homes of substandard quality‡ 1/9 (11) 23/64 (36) 0.44
Mean age of household members, y 28 (23–32) 26 (21–30) 0.39
Duration between first and last isolate obtained from household, d 389 (167–724) 345 (204–599) 0.92

*Values are median (interquartile range) or no. positive/no. tested (%). MDR TB, multidrug-resistant tuberculosis.
†Households classified as having repeated MDR TB introductions for these analyses are indicated in Table A1 (
‡Substandard housing was defined as a dwelling with a dirt floor; walls made of straw matting, plastic, or plywood; a roof made of straw matting, plastic, or plywood; or no access to water in the home (data were not available for all households).

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