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Volume 18, Number 1—January 2012

Research

Serious Invasive Saffold Virus Infections in Children, 2009

Alex Christian Yde NielsenComments to Author , Blenda Böttiger, Jytte Banner, Thomas Hoffmann, and Lars Peter Nielsen
Author affiliations: University of Southern Denmark, Odense, Denmark (A.C.Y. Nielsen); Statens Serum Institut, Copenhagen, Denmark (A.C.Y. Nielsen, B. Böttiger, L.P. Nielsen); University of Aarhus, Aarhus, Denmark (J. Banner); Hvidovre Hospital, Copenhagen (T. Hoffmann)

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Table A1

Laboratory results for 2 children with Saffold virus infection, Denmark, 2009

Analysis Child 1†
Child 2‡
Spinal fluid Blood Feces Spinal fluid Blood Myocardial tissue Pericardial fluid Lung tissue Respiratory samples Feces
Biochemistry
Albumin 0.09 g/L
C-reactive protein <6 mg/L
Creatinine 41 µmol/L
Glucose 3.6 mmol/L
Hemoglobin 7.8 mmol/L
IgG 5.8 g/L
Thrombocytes 301 × 109/L
Protein 0.14 g/L
Sodium 140 mmol/L
Erythrocytes 0 × 106/L
Leukocytes 8 × 106/L 8.4 × 109/L
Culture: bacteria Negative CNS A few NHS A few NHS and Staphlylococcus aureus VTEC
ELISA
Borrelia burgdorferi Negative IgM and IgG
Endomysium antibodies Negative
Epstein Barr virus EBNA IgG negative
Haemophilus influenzae type b 0.62 µg/mL
Legionella pneumophilae Negative IgM and IgG
Mycoplasma pneumoniae Negative IgM and IgG
Intrathecal synthesis
Borrelia burgdorferi Negative
Herpes simplex virus Negative Negative
Ig Negative
Varicella zoster virus Negative Negative
PCR
Adenovirus Negative Negative Negative Negative Negative
Chlamydophila pneumoniae Negative
Chlamydophila psittaci Negative
Coronavirus Negative
Enterovirus Negative Negative Negative Negative Negative Negative
Epstein Barr virus Negative Negative Negative
Herpes simplex virus Negative Negative Negative
Influenza viruses Negative
Legionella pneumophilae Negative
Metapneumovirus Negative
Mycoplasma pneumoniae Negative
Neisseria meningitidis Negative
Parainfluenza viruses Negative
Parechovirus Negative Positive Negative Negative Negative Negative
Parotitis virus Negative Negative
Parvovirus Negative Negative
Respiratory syncytial virus Negative
Rhinovirus Negative
Streptococcus pneumoniae Negative
Varicella zoster virus Negative Negative Negative

*–, not tested or not relevant; CNS, coagulase-negative staphylococci; NHS, nonhemolytic streptococci; VTEC, verotoxin-producing Escherichia coli.
†Previously healthy16-month-old boy who became ill in May 2009.
‡Previously healthy 27-month-old girl who was found dead in her bed in August 2009.

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