Volume 18, Number 1—January 2012
Research
Serious Invasive Saffold Virus Infections in Children, 2009
Alex Christian Yde Nielsen
, Blenda Böttiger, Jytte Banner, Thomas Hoffmann, and Lars Peter Nielsen
, Blenda Böttiger, Jytte Banner, Thomas Hoffmann, and Lars Peter NielsenTable A1
Laboratory results for 2 children with Saffold virus infection, Denmark, 2009
| Analysis | Child 1† |
Child 2‡ |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Spinal fluid | Blood | Feces | Spinal fluid | Blood | Myocardial tissue | Pericardial fluid | Lung tissue | Respiratory samples | Feces | ||
| Biochemistry | |||||||||||
| Albumin | 0.09 g/L | – | – | – | – | – | – | – | – | – | |
| C-reactive protein | – | <6 mg/L | – | – | – | – | – | – | – | – | |
| Creatinine | – | 41 µmol/L | – | – | – | – | – | – | – | – | |
| Glucose | 3.6 mmol/L | – | – | – | – | – | – | – | – | – | |
| Hemoglobin | – | 7.8 mmol/L | – | – | – | – | – | – | – | – | |
| IgG | – | 5.8 g/L | – | – | – | – | – | – | – | – | |
| Thrombocytes | – | 301 × 109/L | – | – | – | – | – | – | – | – | |
| Protein | 0.14 g/L | – | – | – | – | – | – | – | – | – | |
| Sodium | – | 140 mmol/L | – | – | – | – | – | – | – | – | |
| Erythrocytes | 0 × 106/L | – | – | – | – | – | – | – | – | – | |
| Leukocytes | 8 × 106/L | 8.4 × 109/L | – | – | – | – | – | – | – | – | |
| Culture: bacteria | Negative | – | – | CNS | – | – | A few NHS | A few NHS and Staphlylococcus aureus | – | VTEC | |
| ELISA | |||||||||||
| Borrelia burgdorferi | – | Negative IgM and IgG | – | – | – | – | – | – | – | – | |
| Endomysium antibodies | – | – | – | – | Negative | – | – | – | – | – | |
| Epstein Barr virus | – | EBNA IgG negative | – | – | – | – | – | – | – | – | |
| Haemophilus influenzae type b | – | – | – | – | 0.62 µg/mL | – | – | – | – | – | |
| Legionella pneumophilae | – | Negative IgM and IgG | – | – | – | – | – | – | – | – | |
| Mycoplasma pneumoniae | – | Negative IgM and IgG | – | – | – | – | – | – | – | – | |
| Intrathecal synthesis | |||||||||||
| Borrelia burgdorferi | Negative | – | – | – | – | – | – | – | – | – | |
| Herpes simplex virus | Negative | – | – | Negative | – | – | – | – | – | – | |
| Ig | Negative | – | – | – | – | – | – | – | – | – | |
| Varicella zoster virus | Negative | – | – | Negative | – | – | – | – | – | – | |
| PCR | |||||||||||
| Adenovirus | Negative | – | Negative | – | Negative | Negative | – | – | Negative | – | |
| Chlamydophila pneumoniae | – | – | – | Negative | – | – | – | – | – | – | |
| Chlamydophila psittaci | – | – | – | Negative | – | – | – | – | – | – | |
| Coronavirus | – | – | – | – | – | – | – | – | Negative | – | |
| Enterovirus | Negative | – | Negative | Negative | Negative | Negative | – | – | – | Negative | |
| Epstein Barr virus | Negative | Negative | – | – | Negative | – | – | – | – | – | |
| Herpes simplex virus | Negative | Negative | – | Negative | – | – | – | – | – | – | |
| Influenza viruses | – | – | – | – | – | – | – | – | Negative | – | |
| Legionella pneumophilae | – | – | – | Negative | – | – | – | – | – | – | |
| Metapneumovirus | – | – | – | – | – | – | – | – | Negative | – | |
| Mycoplasma pneumoniae | – | – | – | Negative | – | – | – | – | – | – | |
| Neisseria meningitidis | – | – | – | Negative | – | – | – | – | – | – | |
| Parainfluenza viruses | – | – | – | – | – | – | – | – | Negative | – | |
| Parechovirus | Negative | – | Positive | Negative | Negative | Negative | – | – | – | Negative | |
| Parotitis virus | Negative | Negative | – | – | – | – | – | – | – | – | |
| Parvovirus | – | – | – | – | Negative | Negative | – | – | – | – | |
| Respiratory syncytial virus | – | – | – | – | – | – | – | – | Negative | – | |
| Rhinovirus | – | – | – | – | – | – | – | – | Negative | – | |
| Streptococcus pneumoniae | – | – | – | Negative | – | – | – | – | – | – | |
| Varicella zoster virus | Negative | Negative | – | Negative | – | – | – | – | – | – | |
*–, not tested or not relevant; CNS, coagulase-negative staphylococci; NHS, nonhemolytic streptococci; VTEC, verotoxin-producing Escherichia coli.
†Previously healthy16-month-old boy who became ill in May 2009.
‡Previously healthy 27-month-old girl who was found dead in her bed in August 2009.
