Volume 18, Number 2—February 2012
CME ACTIVITY
Invasive Pneumococcal Disease and Pandemic (H1N1) 2009, Denver, Colorado, USA
George E. Nelson
, Kenneth A. Gershman, David L. Swerdlow, Bernard W. Beall, and Matthew R. Moore
, Kenneth A. Gershman, David L. Swerdlow, Bernard W. Beall, and Matthew R. MooreTable 1
Epidemiologic characteristics of patients with invasive pneumococcal disease, Denver, Colorado, USA, February and October 2009*
| Characteristic | Patients with pandemic (H1N1) 2009, Oct 2009, n = 58 | Patients with seasonal influenza, Feb 2009, n = 45 | p value |
|---|---|---|---|
| Age, y | |||
| 0–<5 | 6 (10) | 0 (0) | NC |
| 5–19 | 3 (5) | 3 (7) | NC |
| 20–39 | 10 (17) | 6 (13) | NC |
| 40–59 | 26 (45) | 17 (38) | NC |
| >60 | 13 (22) | 19 (42) | NC |
| Median age (range 2 mo–91 y) | 45 | 54 | 0.02 |
| Sex | 0.120 | ||
| M | 38 (66) | 26 (58) | NC |
| F | 20 (34) | 16 (36) | NC |
| Unknown | 0 | 3 (7) | NC |
| Race† | 0.012 | ||
| White | 31 (53) | 11 (24) | NC |
| African American | 4 (7) | 3 (7) | NC |
| Asian | 0 (0) | 2 (4) | NC |
| Unknown | 23 (40) | 29 (64) | NC |
| Ethnicity† | <0.0001 | ||
| Hispanic | 14 (24) | 7 (16) | NC |
| Non-Hispanic | 25 (43) | 4 (9) | NC |
| Unknown | 19 (33) | 34 (76) | NC |
| Concurrent condition‡ | NC | ||
| Any | 40 (69) | 17 (38) | <0.0001 |
| Chronic lung disease | 17 (29) | 3 (7) | 0.0002 |
| Diabetes | 5 (9) | 6 (13) | 0.852 |
| HIV infection | 2 (3) | 0 (0) | 0.247 |
| Liver disease | 5 (8.6) | 2 (4) | 0.276 |
| Smoking | 15 (26) | 10 (22) | 0.669 |
| Hospitalized | |||
| Yes | 54 (93) | 36 (80) | 0.536 |
| No | 4 (7) | 2(4) | NC |
| Unknown | 0 | 7 (16) | NC |
| Tested for influenza§ | 47 (81) | NA | NC |
| Outpatient setting | 8 | NA | NC |
| Inpatient setting | 43 | NA | NC |
| Positive test result for influenza§ | 10 | NA | NC |
*Values are no. (%) unless otherwise indicated. NA, not available; NC, not calculated.
†Race and ethnicity data required additional patient consent.
‡Underlying concurrent condition comparisons were adjusted for age.
§Includes data from supplemental case report form not available for prior years.
