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Volume 18, Number 2—February 2012

Letter

Zika Virus Infection, Cambodia, 2010

Vireak Heang, Chadwick Y. Yasuda, Ly Sovann, Andrew D. Haddow, Amelia P Travassos da Rosa, Robert B. Tesh, and Matthew R. Kasper1Comments to Author 
Author affiliations: US Naval Medical Research Unit No. 2, Phnom Penh, Cambodia (V. Heang, C.Y. Yasuda); Ministry of Health, Phnom Penh (L. Sovann); University of Texas Medical Branch, Galveston, Texas, USA (A.D. Haddow, A.P. Travassos da Rosa, R.B. Tesh); US Naval Medical Research Unit No. 2, Jakarta, Indonesia (M.R. Kasper)

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Table

Reported or observed clinical signs and symptoms in persons with Zika virus infection, 1962–2010

Sign or symptom Country, year of infection origin,* no. (%) patients
Uganda, 1962, n = 1 Laboratory acquired, 1973, n = 1 Indonesia,
1977–1978, n = 7 Micronesia, 2007, n = 28 Senegal/United States, 2009, n = 3 Cambodia, 2010, n = 1
Fever 1 (100) 1 (100) 7 (100) 20 (65) 1 (100)
Headache 1 (100) 14 (45) 3 (100) 1 (100)
Malaise 1 (100) 5 (71) 3 (100)
Maculopapular rash 1 (100) 28 (100) 3 (100)
Fatigue or myalgia 1 (100) 1 (100) 1 (14) 14 (45) 1 (33)
Arthritis and arthralgia 1 (14) 20 (65) 3 (100)
Chills 1 (100) 2 (29) 2 (67)
Dizziness 5 (71)
Joint swelling or edema 6 (19) 2 (67)
Stomachache 6 (86)
Retro-orbital pain 1 (100) 12 (39)
Conjunctivitis 1 (14) 17 (55) 1 (33)
Anorexia 4 (57)
Photophobia 1 (33)
Vomiting 1 (14) 3 (10)
Diarrhea 3 (43)
Constipation 3 (43)
Sore throat 1 (100)
Cough 1 (100)
Aphthous ulcer 2 (67)
Hypotension 2 (29)
Hematuria 1 (14)
Prostatitis 1 (33)
Hematospermia 1 (33)
Sweating 1 (100)
Lightheadedness 1 (33)

*References: Uganda (2), laboratory-acquired (10), Indonesia (5), Micronesia (9), Senegal/United States (4). Blank cells indicate no reported information.

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1Current affiliation: US Naval Medical Research Unit No. 6, Lima, Peru.

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