Emerging Infectious Disease ISSN: 1080-6059

Lineage-specific Virulence Determinants of Haemophilus influenzae Biogroup aegyptius

Fiona R. Strouts¹, Peter Power, Nicholas J. Croucher, Nicola Corton, Andries van Tonder, Michael A. Quail, Paul R. Langford, Michael J. Hudson, Julian Parkhill, J. Simon Kroll

, and Stephen D. Bentley

Author affiliations: Imperial College London, London, UK (F.R. Strouts, P.R. Langford, J.S. Kroll); University of Oxford, Oxford, UK (P. Power); Wellcome Trust Sanger Institute, Cambridge, UK (N.J. Croucher, N. Corton, A. van Tonder, M.A. Quail, J. Parkhill, S.D. Bentley); The Health Protection Agency, Salisbury, UK (M.J. Hudson)

Main Article

Figure 5

Phylogenetic relatedness of HmwA binding domain. Neighbor-joining tree based on the predicted binding domain of the HmwA adhesins from the indicated nontypeable Haemophilus influenzae (NTHI) strains, constructed by using MEGA5.02 (25). Bootstrap confidence values are shown at the branches, based on 1,000 replications. The population divides into 2 major clusters; HmwA alleles from nontypeable H. influenzae strains are clearly separated from H. influenzae biogroup aegyptius (Hae).

Figure 5. Phylogenetic relatedness of HmwA binding domain. Neighbor-joining tree based on the predicted binding domain of the HmwA adhesins from the indicated nontypeable Haemophilus influenzae (NTHI) strains, constructed by using MEGA5.02 (25). Bootstrap confidence values are shown at the branches, based on 1,000 replications. The population divides into 2 major clusters; HmwA alleles from nontypeable H. influenzae strains are clearly separated from H. influenzae biogroup aegyptius (Hae).

Main Article

¹Current affiliation: Stanford University, Palo Alto, California, USA.

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