Drug Susceptibility of Mycobacterium tuberculosis Beijing Genotype and Association with MDR TB
Jurriaan E.M. de Steenwinkel , Marian T. ten Kate, Gerjo J. de Knegt, Kristin Kremer, Rob E. Aarnoutse, Martin J. Boeree, Henri A. Verbrugh, Dick van Soolingen, and Irma A.J.M. Bakker-Woudenberg
Author affiliations: Erasmus University Medical Center, Rotterdam, the Netherlands (J.E.M. de Steenwinkel, M.T. ten Kate, G.J. de Knegt, H.A. Verbrugh, I.A.J.M. Bakker-Woudenberg); National Institute of Public Health and the Environment Center for Infectious Disease Control (RIVM),; Bilthoven, the Netherlands (K. Kremer, D. van Soolingen); World Health Organization Regional Office for Europe, Copenhagen, Denmark (K. Kremer); Radboud University Nijmegen Medical Center, Nijmegen, the Netherlands (R.E. Aarnoutse, M.J. Boeree, D. van Soolingen)
Figure 1. Frequency of rifampin (RIF)-resistant mutants in Mycobacterium tuberculosis Beijing and East-African/Indian (EAI) genotype strains (5 strains each) originating from Vietnam. Mutation frequencies were determined in duplicate. Statistical analysis was performed by using an unpaired Mann-Whitney test.
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