Volume 18, Number 5—May 2012
CME ACTIVITY
Risk Factors for Intestinal Invasive Amebiasis in Japan, 2003–2009
Naoyoshi Nagata
, Takuro Shimbo, Junichi Akiyama, Ryo Nakashima, So Nishimura, Tomoyuki Yada, Koji Watanabe, Shinichi Oka, and Naomi Uemura
, Takuro Shimbo, Junichi Akiyama, Ryo Nakashima, So Nishimura, Tomoyuki Yada, Koji Watanabe, Shinichi Oka, and Naomi UemuraTable 2
Risk factors for amebic colitis among HIV-positive and -negative patients, Japan, 2003–2009*
| Risk factor | HIV-positive patients |
HIV-negative patients |
p value for interaction | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Amebic colitis, n = 31 | No amebic colitis, n = 217 | OR (95% CI) | p value | Amebic colitis, n = 23 | No amebic colitis, n = 10,659 | OR (95% CI) | p value | ||||
| Age, y | |||||||||||
| >50 | 6 | 83 | Referent | 9 | 8,777 | Referent | |||||
| <50 | 25 | 134 | 2.6 (1.0–8.0) | 0.04 | 14 | 1,882 | 7.3 (2.9–19.0) | <0.01 | 0.11 | ||
| Sex | |||||||||||
| F | 0 | 21 | Referent | 2 | 4499 | Referent | |||||
| M | 31 | 196 | 4.6† (0.8–∞) | 0.11† | 21 | 6,160 | 7.7 (1.9–67.5) | <0.01 | 0.56 | ||
| HBV infection | |||||||||||
| Negative | 26 | 189 | Referent | 21 | 10,510 | Referent | |||||
| Positive | 5 | 28 | 1.3 (0.4–3.8) | 0.62 | 2 | 149 | 6.7 (0.8–27.9) | <0.01 | 0.07 | ||
| Syphilis | |||||||||||
| Negative | 16 | 163 | Referent | 21 | 10,464 | Referent | |||||
| Positive | 15 | 54 | 2.8 (1.2–6.5) | <0.01 | 2 | 195 | 5.1 (0.6–21.1) | 0.01 | 0.48 | ||
| Sexual preference | |||||||||||
| Heterosexual | 3 | 73 | Referent | ND | ND | ND | ND | ND | |||
| MSM | 28 | 144 | 4.7 (1.4–25.0) | <0.01 | ND | ND | ND | ND | ND | ||
| CD4 cell count/μL | |||||||||||
| >300 | 14 | 82 | Referent | ND | ND | ND | ND | ND | ND | ||
| 201–300 | 5 | 31 | 0.9 (0.3–2.8) | ND | ND | ND | ND | ND | ND | ||
| 100–200 | 9 | 39 | 1.35 (0.5–3.4) | ND | ND | ND | ND | ND | ND | ||
| <100 | 3 | 65 | 0.3 (0.07–1.0) | 0.15 | ND | ND | ND | ND | ND | ||
*OR, odds ratio; HBV, hepatitis B virus; ND, no applicable data; MSM, men who have sex with men.
†Analysis by using exact logistic regression model because number in cell was 0.
