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Volume 18, Number 8—August 2012


blaNDM-1–positive Klebsiella pneumoniae from Environment, Vietnam

Rie IsozumiComments to Author , Kumiko Yoshimatsu, Tetsu Yamashiro, Futoshi Hasebe, Binh Minh Nguyen, Tuan Cuong Ngo, Shumpei P. Yasuda, Takaaki Koma, Kenta Shimizu, and Jiro Arikawa
Author affiliations: Hokkaido University, Sapporo, Japan (R. Isozumi, K. Yoshimatsu, S.P. Yasuda, T. Koma, K. Shimizu, J. Arikawa); Nagasaki University, Nagasaki, Japan (T. Yamashiro, F. Hasebe); and National Institute of Hygiene and Epidemiology, Hanoi, Vietnam (B.M.. Nguyen, T.C. Ngo)

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Resistance to 13 antimicrobial drugs of blaNDM-1–positive Klebsiella pneumoniae isolates from the Kim Nguu River, Hanoi, Vietnam*

Antimicrobial drug MIC, mg/L
Site X Site Y
Piperacillin/tazobactam 64–>256 64–>256
Cefotaxime 48–>256 96–128
Ceftazidime >256 >256
Ceftriaxone 96–>256 128–>256
Meropenem 8–>32 12–>32
Doripenem 4–>32 8–>32
Imipenem 6–>32 >32
Fosfomycin 3–8 8
Gentamicin >1,024 >1,024
Tobramycin 384–>1,024 256–384
Ciprofloxacin 0.064–1.5 0.064
Colistin 0.19–2 0.125–0.38
Tgecycline 1.5–3 0.5–1.5

*MICs were interpreted by using Clinical and Laboratory Standards Institute guidelines (

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