Volume 18, Number 8—August 2012
Dispatch
Severe Human Granulocytic Anaplasmosis Transmitted by Blood Transfusion
Matjaz Jereb
, Blaz Pecaver, Janez Tomazic, Igor Muzlovic, Tatjana Avsic-Zupanc, Tanja Premru-Srsen, Snezna Levicnik-Stezinar, Primoz Karner, and Franc Strle
, Blaz Pecaver, Janez Tomazic, Igor Muzlovic, Tatjana Avsic-Zupanc, Tanja Premru-Srsen, Snezna Levicnik-Stezinar, Primoz Karner, and Franc StrleTable 2
Results of PCR and IFA for IgG against Anaplasma. phagocytophilum for index patient and blood donor, Slovenia, 2010*
| Date, 2010 |
Patient
|
Donor
|
|||||
|---|---|---|---|---|---|---|---|
| PCR | IFA | Remarks | PCR | IFA | Remarks | ||
| May 12† | – | – | 118 d before index donation | ||||
| Aug 28–29 | ND | ND | Febrile illness | ||||
| Sep | |||||||
|
7† |
+ | >1,024 | Index donation | ||||
|
15 |
– | – | Transfusion | ||||
|
25 |
ND | ND | Onset of febrile illness | ||||
| Oct | |||||||
|
1 |
+‡ | – | Treatment with doxycycline Oct 1–14 | ||||
|
4 |
+ | 128 | |||||
|
6 |
+ | 512 | |||||
|
9 |
+ | ND | |||||
|
10 |
– | ND | |||||
|
12 |
– | 512 | |||||
|
19 |
ND | 512 | |||||
|
20 |
– | >1,024 | 43 d after index donation | ||||
| Nov 23 | ND | >1,024 | No reports of problems | ||||
*Results for IFA are shown in titers. IFA, immunofluorescence assay; ND, not done; –, negative; +, positive.
†Retrospective testing of stored blood specimen.
‡DNA detected in stored bone marrow–biopsy specimen.
