Figure. . . IPD clinical cases in PCV7-eligible children since PCV7 introduction, England and Wales, September 4, 2006–March 31, 2010. A) Distribution of cases. Black bar sections, bacteremia; dark gray bar sections, lower respiratory tract infection; light gray bar sections, meningitis; white bar sections, other. B) Proportion of serotyped cases caused by PCV7 serotypes in healthy children (dashed line) and children with comorbidities (solid line). The prevalences of comorbidity among IPD cases during the 4 time periods were 13,5%, 17.7%, 17.0%, and 10.7%, and the case-fatality rates were 5.6%, 4.3%, 4.3%, and 3.0%, respectively. *Data included for 7 months only. IPD, invasive pneumococcal disease; PCV7, 7-valent pneumococcal conjugate vaccine.
The opinions expressed by authors contributing to this journal do not necessarily reflect the opinions of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.