Novel Polyomavirus associated with Brain Tumors in Free-Ranging Raccoons, Western United States
Florante N. Dela Cruz, Federico Giannitti, Linlin Li, Leslie W. Woods, Luis Del Valle, Eric Delwart, and Patricia A. Pesavento
Author affiliations: Author affiliations: University of California, Davis, Davis, California, USA (F.N. Dela Cruz, Jr., F. Giannitti, L.W. Woods, P.A. Pesavento); Blood Systems Research Institute, San Francisco, California, USA (L. Li, E. Delwart); Louisiana State University, New Orleans, Louisiana, USA (L. Del Valle); University of California, San Francisco, San Francisco (E. Delwart)
Figure 2. . Genome organization of RacPyV. The entire dsDNA viral genome for RacPyV10 comprises 5,015 bp. The viral genome has a noncoding regulatory region and putative open reading frames for the late proteins VP1, VP2, and VP3 and the early proteins LT-Ag and sT-Ag. MCPyV and GorPyV, which are phylogenetic neighbors, and SV40 are presented for comparison. RacPyV, raccoon polyomavirus; LT-Ag, large T-antigen; sT-Ag, small T-antigen; VP, viral protein; MCPyV, Merkel cell polyomavirus; SV40, simian virus 40. GorPyV, gorilla polyomavirus.
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