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Volume 19, Number 1—January 2013

Dispatch

Novel Epidemic Clones of Listeria monocytogenes, United States, 2011

Sara Lomonaco, Bindhu Verghese, Peter Gerner-Smidt, Cheryl Tarr, Lori Gladney, Lavin Joseph, Lee Katz, Maryann Turnsek, Michael Frace, Yi Chen, Eric Brown, Richard Meinersmann, Mark Berrang, Stephen KnabelComments to Author , and Authors
Author affiliations: Author affiliations: Università degli Studi di Torino, Turin, Italy (S. Lomonaco); Accugenix, Newark, Delaware, USA (B. Verghese); The Pennsylvania State University, University Park, Pennsylvania, USA (B. Verghese, S. Knabel); Centers for Disease Control and Prevention, Atlanta, Georgia, USA (P. Gerner-Smidt, C. Tarr, L. Gladney, L. Joseph, L. Katz, M. Turnsek, M. Frace); Food and Drug Administration, College Park, Maryland, USA (Y. Chen, E. Brown); US Department of Agriculture, Athens, Georgia, USA (R. Meinersmann, M. Berrang)

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Table

Characteristics of Listeria monocytogenes isolates representing 1 novel outbreak strain and 2 newly defined epidemic clones, ECVI and ECVII, United States, 2011*

Isolate† Agency Outbreak year, location, source (type of source) Serotype MLST ST (CC) MVLST
VT (EC) UP PT DOWN PT
PFGE profile1‡

L2624

CDC 2011, US, cantaloupe (C) 1/2b 5 (5) 63 (VI)

LIS0075

FDA 2011, US, cantaloupe (F) 1/2b 5 (5) 63 (VI)

LIS0078

FDA 2011, US, cantaloupe (E) 1/2b 5 (5) 63 (VI)

233

USDA 2002, US, chicken plant A (F) 1/2b 5 (5) 63 (VI)

466

USDA 2006, US, chicken plant B (F) 1/2b 5 (5) 63 (VI) 11

10–0810

NML 1996, Canada, imitation crabmeat (C) 1/2b 5 (5) 63 (VI) 11 11

10–0811


NML
1996, Canada, imitation crabmeat (F)
1/2b
5 (5)
63 (VI)
11
11
PFGE profile 2

L2625


CDC
2011, US, cantaloupe (C)
1/2a
29 (29)
74


PFGE profile 3

L2626

CDC 2011, US cantaloupe (C) 1/2a 561 (7)§ 56 (VII)

LIS0077


FDA
2011 US, cantaloupe (E)
1/2a
561 (7)
56 (VII)


PFGE profile 4

L2676

CDC 2011, US, cantaloupe (C) 1/2a 7 (7) 56 (VII) 18 13

LIS0072

FDA 2011, US, cantaloupe (F) 1/2a 7 (7) 56 (VII) 18 13

LIS0087

FDA 2011, US, cantaloupe (E) 1/2a 7 (7) 56 (VII) 18 13

261

USDA 2002, US, chicken plant A (E) 1/2a 7 (7) 56 (VII) 18 13

498

USDA 2006, US, chicken plant B (E) 1/2a 7 (7) 56 (VII) 10

10–813

NML 2000 Canada, whipping cream (C) 1/2a 7 (7) 56 (VII) 13

10–812

NML 2000 Canada, whipping cream (F) 1/2a 7 (7) 56 (VII) 13

*For comparison, additional molecular subtype data from unrelated foodborne outbreaks in Canada were obtained (4). PFGE, pulsed-field gel electrophoresis; CDC, Centers for Disease Control and Prevention; FDA, Food and Drug Administration; USDA, US Department of Agriculture; NML, National Microbiology Laboratory of Canada, Division of the Public Health Agency of Canada; MLST ST (CC), multilocus sequence typing, sequence type (clonal complex); MVLST VT (EC), multivirulence locus sequence typing, virulence type (epidemic clone); UP PT, upstream comK prophage type; DOWN PT, downstream comK prophage type; –, no PCR amplification of junction fragment.
†The numbering of outbreak strain used differs from the FDA’s final update on the outbreak (www.fda.gov/Food/FoodSafety/CORENetwork/ucm272372.htm#report).
‡PFGE profiles based on CDC and FDA analysis of isolates from cantaloupe-associated outbreak.
§ST561 differs from ST7 by 1 nonsynonymous single nucleotide polymorphism (G/A) in lhkA.

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