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Volume 19, Number 2—February 2013

Research

Severe Lower Respiratory Tract Infection in Early Infancy and Pneumonia Hospitalizations among Children, Kenya

Patrick Kiio MunywokiComments to Author , Eric O. Ohuma, Mwanajuma Ngama, Evasius Bauni, J. Anthony G. Scott, and D. James Nokes
Author affiliations: Author affiliations: KEMRI-Wellcome Trust Research Programme Centre for Geographic Medicine Research–Coast, Kilifi, Kenya (P.K. Munywoki, E.O. Ohuma, M. Ngama, E. Bauni, J.A.G. Scott, D.J. Nokes); University of Oxford, Oxford, UK (E.O. Ohuma, J.A.G. Scott); University of Warwick, Coventry, UK (D.J. Nokes)

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Table 1

Baseline characteristics of children in study of pneumonia hospitalizations after severe LRTI in infancy, by study group, at time of first admission in Kilifi District Hospital, coastal Kenya, April 16, 2002–May 31, 2010*

Characteristics Initial hospitalization
RSV LRTI, n = 560 Other LRTI, n = 1,140 Non-LRTI, n = 1,113
Male 296 (52.9) 646 (56.7) 607 (54.5)
Median age, mo (IQR) 3.7 (1.9–6.6) 4.6 (2.1–7.7) 4.7 (0.3–8.6)
Children age <3 mo 241 (43.0) 406 (35.6) 489 (43.9)
Median hospital stay, d (IQR) 4 (3–5) 3 (2–5) 4 (2–6)
Malaria† 9 (1.6) 114 (10.0) 147 (13.2)
Gastroenteritis 34 (6.1) 140 (12.3) 338 (30.4)
Pneumonia with wheeze 95 (17.0) 125 (11.0) NA
Bacteremia, no./n (%) 7/545 (1.3) 33/1,109 (3.0) 33/1,053 (3.1)
Admission to high-dependency unit 18 (3.2) 89 (7.8) 79 (7.1)
Good hospital access 326 (59.5) 621 (55.4) 636 (58.6)
Hypoxia 44 (7.9) 95 (8.3) 17 (1.5)

*Values are no. (%) except as indicated. Boldface indicates statistical significance in the respective group relative to the non-LRTI group. RSV, respiratory syncytial virus; LRTI, lower respiratory tract infection; IQR, interquartile range; NA, not applicable.
†Indicates blood slide testing positive for malaria parasites.

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