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Volume 19, Number 5—May 2013
Dispatch

Delayed Diagnosis of Chronic Q Fever and Cardiac Valve Surgery

Linda M. KampschreurComments to Author , Elske Hoornenborg, Nicole H. M. Renders, Jan Jelrik Oosterheert, Joost F. Haverman, Peter Elsman, and Peter C. Wever
Author affiliations: University Medical Center Utrecht, Utrecht, the Netherlands (L.M. Kampschreur, J.J. Oosterheert); Jeroen Bosch Hospital, ‘s-Hertogenbosch, the Netherlands (L.M. Kampschreur, E. Hoornenborg, N,H.M. Renders, J.F. Haverman, P. Elsman, P.C. Wever)

Main Article

Table

Results of Coxiella burnetii and C-reactive protein testing for 3 patients with chronic Q fever and valvular cardiac disease requiring valve surgery, the Netherlands*

Case-patient Results for C. burnetii testing
 C-reactive protein, mg/L
IFA†
 PCR
Phase I IgG titer Phase II IgG titer
1
Before valve surgery† 32,768 65,536 Negative <6
After valve surgery
 8,192
 8,192
 Positive
 52
2
Before valve surgery 16,384 16,384 Positive 22
After valve surgery
 16,384
 16,384
 Positive
 26
3‡
After valve surgery 8,192 8,192 Positive 11

*IFA, immunofluorescence assay.
†Q fever serologic testing was performed retrospectively.
‡Serologic testing was not available before surgery.

Main Article

Page created: April 23, 2013
Page updated: April 23, 2013
Page reviewed: April 23, 2013
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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