Molecular Epidemiologic Source Tracking of Orally Transmitted Chagas Disease, Venezuela
Maikell Segovia, Hernán J. Carrasco , Clara E. Martínez, Louisa A. Messenger, Anaibeth Nessi, Juan C. Londoño, Raul Espinosa, Cinda Martínez, Mijares Alfredo, Rafael Bonfante-Cabarcas, Michael D. Lewis, Belkisyolé A. de Noya, Michael A. Miles, and Martin S. Llewellyn
Author affiliations: Universidad Central de Venezuela Instituto de Medicina Tropical, Caracas, Venezuela (M. Segovia, H.J. Carrasco, C.E. Martínez, A. Nessi, B.A. de Noya); London School of Hygiene and Tropical Medicine, London, UK (L.A. Messenger, M.D. Lewis, M.A. Miles, M.S. Llewellyn); Universidad Central de Venezuela, Caracas (J.C. Londoño); Instituto Venezolano de los Seguros Sociales, Caracas (R. Espinosa); Instituto Venezolano de Investigaciones Científicas, Caracas (M. Alfredo); Ministerio del Poder Popular para la Salud, Maracay, Estado Aragua, Venezuela (C. Martínez); Universidad Centroccidental Lisandro Alvarado, Barquisimeto, Venezuela (R. Bonfante-Cabarcas)
Figure 2. . Discriminant analysis of principal components showing genetic clustering among Trypanosoma cruzi isolates from 2 outbreaks of oral disease in northern Venezuela. Six principal components were retained, explaining 80% of the diversity. Ellipses correspond to the optimal (as defined by the Bayesian information criterion minimum) number of population clusters among the genotypes analyzed. Images indicate sample host origin (human, rodent, marsupial, or triatomine), while colors correspond to the key in Figure 1. A full list of samples and population assignments (numbered boxes) is included in Technical Appendix 2. Dashed box indicates the isolates associated with the outbreaks.
The opinions expressed by authors contributing to this journal do not necessarily reflect the opinions of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.