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Volume 19, Number 7—July 2013

Dispatch

Molecular Epidemiologic Source Tracking of Orally Transmitted Chagas Disease, Venezuela

Maikell Segovia, Hernán J. CarrascoComments to Author , Clara E. Martínez, Louisa A. Messenger, Anaibeth Nessi, Juan C. Londoño, Raul Espinosa, Cinda Martínez, Mijares Alfredo, Rafael Bonfante-Cabarcas, Michael D. Lewis, Belkisyolé A. de Noya, Michael A. Miles, and Martin S. Llewellyn
Author affiliations: Universidad Central de Venezuela Instituto de Medicina Tropical, Caracas, Venezuela (M. Segovia, H.J. Carrasco, C.E. Martínez, A. Nessi, B.A. de Noya); London School of Hygiene and Tropical Medicine, London, UK (L.A. Messenger, M.D. Lewis, M.A. Miles, M.S. Llewellyn); Universidad Central de Venezuela, Caracas (J.C. Londoño); Instituto Venezolano de los Seguros Sociales, Caracas (R. Espinosa); Instituto Venezolano de Investigaciones Científicas, Caracas (M. Alfredo); Ministerio del Poder Popular para la Salud, Maracay, Estado Aragua, Venezuela (C. Martínez); Universidad Centroccidental Lisandro Alvarado, Barquisimeto, Venezuela (R. Bonfante-Cabarcas)

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Table 1

FST values in a 4-way comparison for differentiation between Trypanosoma cruzi isolates derived from humans and the local environment during an outbreak of orally transmitted Chagas disease in 2 areas of Venezuela*

Isolate, location Human isolates from
Nonhuman isolates from
Antimano Chichiriviche Antimano Chichiriviche
Human
Antimano 0.000 0.000 0.000
Chichiriviche
0.201

0.000
0.004
Nonhuman
Antimano 0.093 0.170 0.000
Chichiriviche 0.088 0.053 0.079

*Lower left shows linearized FST (genetic differentiation) values; upper right shows associated p values.

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