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Volume 8, Number 11—November 2002
THEME ISSUE
Tuberculosis Genotyping

Tuberculosis Genotyping Network, United States

Identifying the Sources of Tuberculosis in Young Children: A Multistate Investigation

Sumi J. Sun*Comments to Author , Diane E. Bennett†, Jennifer Flood*, Ann M. Loeffler*, Steve Kammerer†, and Barbara A. Ellis†
Author affiliations: *California Department of Health Services, Berkeley, California, USA; †Centers for Disease Control and Prevention, Atlanta, Georgia, USA;

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Table 6

Characteristics of source patients in confirmed patient pairsa

Source patient characteristics Confirmed sources for secondary patients <5 yrs of age
n=44 (%) Confirmed sources for secondary patients ≥15 ys of age
n=240 (%)
Mean age, yrs 31 38
Female 18 (41) 103 (43)
Race/ethnicityb
Black, non-Hispanic 20 (45) 148 (62)
Hispanic 17 (39) 23 (10)
Asian 5 (11) 19 (8)
White, non-Hispanic 0 48 (20)
Native American or Alaskan Native 2 (5) 2 (1)
Foreign-bornc 20 (45) 56 (23)
Bacteriologic results, sputumd
Smear positive/culture positive 34 (81) 200 (85)
Smear negative/culture positive 8 (19) 33 (14)
Smear negative/culture negative 0 1 (<1)
Cavitary chest radiographe 27 (64) 125 (53)
Provider typef
Health department 25 (57) 141 (60)
Private provider 9 (20) 43 (18)
Both 10 (23) 52 (22)
Directly observed therapy b,g 30 (68) 198 (84)
Previous diagnosis of TBh 6 (14) 27 (11)
Shared household with secondary case b,i 32 (91) 116 (50)

aConfirmed patient pairs include source patients who transmitted TB to young children and source patients who transmitted TB to adolescent and adult patients.
bChi-square statistic, p<0.05.
cCountry of origin unknown for one patient.
dExcludes eight patients in whom either the culture or smear was not done.
eChest radiograph results unknown for two patients.
fProvider type unknown for four patients.
gCompared to patients on self-administered therapy only. Directly observed therapy status unknown for six patients.
hHistory of TB unknown for two patients.
iRelationship to secondary case unknown for 19 patients.

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