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Volume 8, Number 2—February 2002


Community-Acquired Klebsiella pneumoniae Bacteremia: Global Differences in Clinical Patterns

Wen-Chien Ko*, David L. Paterson†‡, Anthanasia J. Sagnimeni‡, Dennis S. Hansen§, Anne von Gottberg¶, Sunita Mohapatra#, Jose Maria Casellas**, Herman Goossens††, Lutfiye Mulazimoglu‡‡, Gordon Trenholme#, Keith P. Klugman¶, Joseph G. McCormack‡, and Victor L. Yu†Comments to Author 
Author affiliations: *National Cheng Kung University Medical College, Taiwan; †Veterans Administration Medical Center and University of Pittsburgh, Pittsburgh, Pennsylvania, USA; ‡University of Queensland, Mater Adults Hospital, Brisbane, Australia; §Statens Serum Institut, Copenhagen, Denmark; ¶South African Institute of Medical Research, Johannesburg, South Africa; #Rush-Presbyterian-St. Luke’s Medical Center, Chicago, Illinois, USA; **Sanatorio San Lucas, Buenos Aires, Argentina; ††University Hospital, Antwerp, Belgium; ‡‡Marmara University, Istanbul, Turkey;

Main Article

Table 4

Comparison of the characteristics of patients with distinctive infections associated with community-acquired Klebsiella pneumoniae bacteremia (liver abscess, meningitis, and endophthalmitis) and other patients with community-acquired K. pneumoniae bacteremia: association with diabetes mellitus and residence in Taiwan

Characteristic Liver abscess, endophthalmitis or meningitis
 (n=25) Other community-acquired bacteremia (n=177) p-valuea
Resides in Taiwan 22 (88%) 74 (42%) 0.0001
Age (years) 55.5 57.4 NS
Serum creatinineb (mg/dL) 2.2 2.2 NS
Blood urea nitrogen* (mg/dL) 35.7 37.2 NS
Underlying disease
Diabetes mellitus (%) 15 (60%) 50 (28%) 0.0015
Chronic renal failure (%) 3 (12%) 11 (6%) NS
Underlying liver disease (%) 5 (20%) 46 (26%) NS
Chronic hepatitis B virus infection 0 9 (5%) NS
Hepatitis C virus infection (%) 1 (4%) 8 (5%) NS
Alcoholism (%) 2 (8%) 14 (8%) NS
Malignancy (%) 0 43 (24%) 0.006
No underlying disease 6 (24%) 61 (34%) NS
Critically illc 9 (36%) 35 (20%) 0.07
Death rate at 14 days (%) 8 (32%) 54 (31%) NS

aNS = p >0.20.

bLaboratory values are those taken on first visit to a health-care provider; for continuous variables, the figures in the table are mean values.

cCritically ill defined as Pitt bacteremia score ≥4.

Main Article

1United States: Pittsburgh Veterans Affairs Medical Center, Pittsburgh, Pennsylvania, and Rush-Presbyterian-St. Luke’s Medical Center, Chicago, Illinois; Taiwan: National Cheng Kung University Medical College, Tainan; Australia: Royal Brisbane Hospital, Mater Adults Hospital, and Greenslopes Private Hospital, all in Brisbane; South Africa: Hillbrow Hospital and Baragwanath Hospital, both in Johannesburg; Turkey: Marmara University Hospital, Istanbul; Belgium: University Hospital, Antwerp; and Argentina: San Lucas Hospital and Comunidad Olivos Hospital, both in Buenos Aires.

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