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Volume 8, Number 3—March 2002

Research

Immunization with Heterologous Flaviviruses Protective Against Fatal West Nile Encephalitis

Robert B. TeshComments to Author , Amelia P.A. Travassos da Rosa, Hilda Guzman, Tais P. Araujo, and Shu-Yuan Xiao
Author affiliations: University of Texas Medical Branch, Galveston, Texas, USA;

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Table 3

Infection and mortality rates, following intraperitoneal inoculation of 104 TCID50 of West Nile virus (WNV), in nonimmune (control) hamsters, and in hamsters previously immunized with Japanese encephalitis (JE) SA14-2-8 vaccine, St. Louis encephalitis virus (SLEV) strain BeAr 23379, or yellow fever (YF) 17D vaccine

Immune group No. infected with WNV No. infected (%)a No. died (%)
Nonimmune 30 30 (100) 14 (47)
JEV SA14-2-8 30 30 (100) 0 (0)
SLEV BeAr 23379 32 32 (100) 0 (0)
YFV 17D 30 30 (100) 4 (13)

a Total number of animals infected or dead after being infected with WNV.

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