Volume 8, Number 3—March 2002
Research
Immunization with Heterologous Flaviviruses Protective Against Fatal West Nile Encephalitis
Robert B. Tesh
, Amelia P.A. Travassos da Rosa, Hilda Guzman, Tais P. Araujo, and Shu-Yuan Xiao
, Amelia P.A. Travassos da Rosa, Hilda Guzman, Tais P. Araujo, and Shu-Yuan XiaoTable 3
Infection and mortality rates, following intraperitoneal inoculation of 104 TCID50 of West Nile virus (WNV), in nonimmune (control) hamsters, and in hamsters previously immunized with Japanese encephalitis (JE) SA14-2-8 vaccine, St. Louis encephalitis virus (SLEV) strain BeAr 23379, or yellow fever (YF) 17D vaccine
| Immune group | No. infected with WNV | No. infected (%)a | No. died (%) |
|---|---|---|---|
| Nonimmune | 30 | 30 (100) | 14 (47) |
| JEV SA14-2-8 | 30 | 30 (100) | 0 (0) |
| SLEV BeAr 23379 | 32 | 32 (100) | 0 (0) |
| YFV 17D | 30 | 30 (100) | 4 (13) |
a Total number of animals infected or dead after being infected with WNV.
