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Volume 9, Number 11—November 2003

Research

Coronavirus-positive Nasopharyngeal Aspirate as Predictor for Severe Acute Respiratory Syndrome Mortality

Owen Tak-Yin Tsang*, Tai-Nin Chau*, Kin-Wing Choi*, Eugene Yuk-Keung Tso*, Wilina Lim†, Ming-Chi Chiu*, Wing-Lok Tong*, Po-Oi Lee*, Bosco Hoi Shiu Lam*, Tak-Keung Ng*, Jak-Yiu Lai*Comments to Author , Wai-Cho Yu*, and Sik-To Lai*Comments to Author 
Author affiliations: *Princess Margaret Hospital, Hong Kong; †Public Health Laboratory Centre, Hong Kong

Main Article

Table 1

Symptoms of 218 patients with severe acute respiratory syndromea

Symptoms Positive RT-PCR for coronavirus
n=156 (%) Negative RT-PCR for coronavirus
n=62 (%) p value
Time from symptoms onset to sample collection (days) 4.5 ± 2.2 4.2 ± 2.4 0.366
Fever 155 (99) 60 (97) 0.139
Chill 120 (77) 51 (82.3) 0.388
Malaise 103 (66) 34 (54.8) 0.123
Myalgia 84 (53.8) 30 (48.4) 0.467
Cough 66 (42.3) 27 (43.5) 0.867
Rigor 65 (41.7) 27 (43.5) 0.800
Headache 49 (31.4) 25 (40.3) 0.210
Anorexia 37 (23.7) 14 (22.6) 0.858
Sputum 28 (18) 13 (21) 0.607
Shortness of breath 36 (23) 5 (8.1) 0.012
Dizziness 23 (14.7) 17 (27.4) 0.029
Diarrhea 22 (14.1) 9 (14.5) 0.937
Sore throat 21 (13.5) 10 (16.1) 0.611
Runny nose 15 (9.6) 9 (14.5) 0.297
Chest pain 13 (8.3) 8 (12.9) 0.302
Vomiting 12 (7.7) 5 (8) 0.926
Palpitation 2 (1.3) 2 (3.2) 0.320
Hemoptysis 1 (0.6) 1 (1.6) 0.497
Confusion 1 (0.6) 1 (1.6) 0.497

aFisher exact test was applied if p value was <5; RT-PCR, reverse transcription polymerase chain reaction; p values in bold are significant.

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