Blood Transfusion and Spread of Variant Creutzfeldt-Jakob Disease
Figure 5. Absolute prevalence of infected donors for an incubation period of 16 (A) and 50 (B) years. The solid black curves show the infected donors without transfusion history. These curves are identical for 0% and 100% infectivity and are independent of donor exclusion. The gray curves show infected donors with transfusion history for 100% (solid) and 0% (dashed) infectivity, respectively, without donor exclusion. The dotted black curves show the effect of donor exclusion starting at the beginning of alimentary risk. Most infected donors have no transfusion history and cannot, therefore, be excluded from blood donation.