Volume 14, Number 8—August 2008
Research
Puumala Hantavirus Excretion Kinetics in Bank Voles (Myodes glareolus)
Jonas Hardestam*†1
, Malin Karlsson*1, Kerstin I. Falk*†, Gert Olsson*‡§, Jonas Klingström*†, and Åke Lundkvist*†
, Malin Karlsson*1, Kerstin I. Falk*†, Gert Olsson*‡§, Jonas Klingström*†, and Åke Lundkvist*†Table 2
Infection of bank voles with PUUV after intranasal inoculation with saliva, urine, and feces samples*
| Inoculum | Bank vole no. | Seropositivity | PUUV RNA in excreta by time, d† | ||||
|---|---|---|---|---|---|---|---|
| Day 21 PI | Day 42 PI | Saliva | Urine | Feces | |||
| Saliva | 1 | – | + | NT | NT | NT | |
| 2 | – | – | NT | NT | NT | ||
| 3 | – | – | NT | NT | NT | ||
| 4 | + | + | 0, 6, 14, 19, 26, 35, 42 | 0, 19, 26, 42 | 0, 6, 14, 19, 26, 35, 42 | ||
| Urine | 5 | – | + | NT | 0, 24, 26, 28 | NT | |
| 6 | – | – | NT | NT | NT | ||
| 7 | – | + | 0, 6, 14, 19, 26, 35, 42 | 0, 14, 19, 35 | 0, 6, 14, 19, 26, 35, 42 | ||
| 8 | – | – | NT | NT | NT | ||
| 9 | – | – | NT | NT | NT | ||
| Feces | 10 | – | + | NT | 6, 14, 24, 26, 35, 42 | NT | |
| 11 | – | – | NT | NT | NT | ||
| 12 | – | + | NT | 0, 24 | NT | ||
| 13 | – | + | 0, 14, 19, 26, 35, 42 | 6, 19, 24 | 0, 6, 19, 26, 35, 42 | ||
| 14 | – | – | NT | NT | NT | ||
*PUUV, Puumala virus; PI, postinfection; –, negative; +, positive; NT, not tested.
†Numbers indicate days PI for tested excretions. Days with positive excretions are shown in boldface.
