Volume 15, Number 7—July 2009
Research
Relapse Associated with Active Disease Caused by Beijing Strain of Mycobacterium tuberculosis1
William J. Burman
, Erin E. Bliven, Lauren Cowan, Lorna Bozeman, Payam Nahid, Lois Diem, Andrew Vernon, and for the Tuberculosis Trials Consortium
, Erin E. Bliven, Lauren Cowan, Lorna Bozeman, Payam Nahid, Lois Diem, Andrew Vernon, and for the Tuberculosis Trials ConsortiumTable 4
Association between active disease caused by a Beijing genotype of Mycobacterium tuberculosis and relapse, by race/ethnic background, Tuberculosis Trials Consortium Study 22*
| Race/ethnicity | Patients with disease that relapsed |
Relapse odds ratio (95% CI) | p value | |
|---|---|---|---|---|
| Infected with a Beijing strain, no. positive/no. tested (%) | Not infected with a Beijing strain, no. positive/no. tested (%) | |||
| Non-Hispanic white (n = 63) | 3/11 (27) | 17/52 (33) | 0.8 (0.2–3.3) | 0.73 |
| Non-Hispanic black (n = 148) | 6/22 (27) | 15/126 (12) | 2.8 (0.9–8.2) | 0.06 |
| Hispanic (n = 79) | 1/7 (14) | 7/72 (9.7) | 1.5 (0.2–15) | 0.70 |
| Asian–Pacific Islander (n = 50) | 4/16 (25) | 1/34 (2.9) | 11 (1.1–108) | 0.04 |
*The Tuberculosis Trials Consortium Study enrolled patients during 1995–1998. Participants in the case–control study were selected from among 1,004 HIV-infected participants. Participants of Native American race/ethnicity (n = 12) were not included because none were infected with a Beijing strain; 2 Native American participants had disease that relapsed. CI, confidence interval.
