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Volume 16, Number 11—November 2010

Research

Lymphotropism of Merkel Cell Polyomavirus Infection, Nova Scotia, Canada

Sonia Toracchio, Annette Foyle, Vojtech Sroller1, Jon A. Reed, Jun Wu, Claudia A. Kozinetz, and Janet S. ButelComments to Author 
Author affiliations: Baylor College of Medicine, Houston, Texas, USA (S. Toracchio, V. Sroller, J.A. Reed, C.A. Kozinez, J.S. Butel); Dalhousie University, Halifax, Nova Scotia, Canada (A. Foyle); Queen Elizabeth II Health Science Center, Halifax (A. Foyle); and Public Health Agency of Canada, Ottawa, Ontario, Canada (J. Wu); 1Current affiliation: Institute of Hematology and Blood Transfusion, Prague, Czech Republic

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Figure

Merkel cell polyomavirus (MCPyV) large T-antigen (T-ag) expression in human tissues. A) Merkel cell carcinoma stained with CM2B4 antibody as a positive control; MCPyV T-ag was detected. B) Expression of MCPyV T-ag in small lymphocytes in an MCPyV DNA–positive angioimmunoblastic T-cell lymphoma, stained with CM2B4. C) MCPyV DNA–positive reactive lymphoid hyperplasia sample reacted with CM2B4; no T-ag was detected. D) MCPyV DNA-negative chronic lymphocytic leukemia/small lymphocytic lymphoma sampl

Figure. Merkel cell polyomavirus (MCPyV) large T-antigen (T-ag) expression in human tissues. A) Merkel cell carcinoma stained with CM2B4 antibody as a positive control; MCPyV T-ag was detected. B) Expression of MCPyV T-ag in small lymphocytes in an MCPyV DNA–positive angioimmunoblastic T-cell lymphoma, stained with CM2B4. C) MCPyV DNA–positive reactive lymphoid hyperplasia sample reacted with CM2B4; no T-ag was detected. D) MCPyV DNA-negative chronic lymphocytic leukemia/small lymphocytic lymphoma sample stained with CM2B4; no T-ag was detected. Original magnification ×40.

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