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Volume 16, Number 11—November 2010

Research

Lymphotropism of Merkel Cell Polyomavirus Infection, Nova Scotia, Canada

Sonia Toracchio, Annette Foyle, Vojtech Sroller1, Jon A. Reed, Jun Wu, Claudia A. Kozinetz, and Janet S. ButelComments to Author 
Author affiliations: Baylor College of Medicine, Houston, Texas, USA (S. Toracchio, V. Sroller, J.A. Reed, C.A. Kozinez, J.S. Butel); Dalhousie University, Halifax, Nova Scotia, Canada (A. Foyle); Queen Elizabeth II Health Science Center, Halifax (A. Foyle); and Public Health Agency of Canada, Ottawa, Ontario, Canada (J. Wu); 1Current affiliation: Institute of Hematology and Blood Transfusion, Prague, Czech Republic

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Table 3

MCPyV infection and characteristics of patients with chronic lymphocytic leukemia/small lymphocytic lymphoma, Nova Scotia, Canada, 1994–2001*

Characteristic No. (%) cases No. (%) MCPyV positive No. (%) MCPyV negative
Patient sex
M 16 (66.7) 2 (12.5) 14 (87.5)
F
8 (33.3)
3 (37.5)
5 (62.5)
Patient age, y
<60 6 (25.0) 0 6 (100.0)
>60
18 (75.0)
5 (27.8)
13 (72.2)
Disease stage†
I 9 (40.9) 1 (11.1) 8 (88.9)
II 5 (22.7) 3 (60.0) 2 (40.0)
III 0 0 0
IV
8 (36.4)
1 (12.5)
7 (87.5)
Patient survival‡
Alive in remission 2 (15.4) 1 (50.0) 1 (50.0)
Alive with disease 6 (46.1) 0 6 (100.0)
Dead from disease
5 (38.5)
1 (20.0)
4 (80.0)
Total 24 5 (20.8) 19 (79.2)

*No patients with chronic lymphocytic leukemia/small lymphocytic lymphoma had Merkel cell carcinoma. MCPyV, Merkel cell polyomavirus.
†Stage of disease for 2 MCPyV-negative patients was unknown.
‡Five-year follow-up survival information. Data were available for 13 patients, excluding 10 who had received a diagnosis within the past 5 y and one who was lost to follow-up. Disease refers to original diagnosis of either lymphoma or leukemia.

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