Volume 17, Number 1—January 2011
Hepatitis E Virus Infection without Reactivation in Solid-Organ Transplant Recipients, France
||Incidence, cases/100 person-years (95% confidence interval)
|All||3.2 (2.06–4.13)||3.5 (1.9–5.1)||1.1 (0.03–2.19)||3.7 (1.09–6.1)||3.0 (0.1–7.52)||0.08|
|Kidney transplant||2.7 (1.52–3.68)||2.4 (0.8–3.9)||0.9 (0.01–4.4)||3.3 (0.47–6.120)||4.3 (1.28–11.48)||0.18|
|Liver transplant||4.8 (2.2–7.4)||7.12 (2.63–11.62)||1.6 (0.04–7.60)||5.1 (0.52–14.54)||0 (0–10)||0.24|
*HEV, hepatitis E virus.
1Based on results from this study, which of the following patients would be anticipated to be at highest risk for acquisition of hepatitis E virus (HEV) infection?
A. A 65-year-old man undergoing kidney transplantation
B. A 45-year-old woman undergoing liver transplantation
C. A 76-year-old man 1 year post liver transplant.
D. A 36-year-old woman 6 months post kidney transplant
2A 49-year-old female patient who is HIV positive undergoes a liver transplant. Six months later she is found to be HEV positive. Which of the following factors would increase her risk to evolve to a chronic infection?
A. Alcohol use
B. Female sex
C. Immunocompromise associated with HIV infection
D. Comorbid hepatitis C virus or hepatitis B virus infection