Volume 17, Number 10—October 2011
Research
Oseltamivir-Resistant Pandemic (H1N1) 2009 Virus Infection in England and Scotland, 2009–2010
Table 3
Distribution of age, sex, underlying medical conditions, and outcomes among persons hospitalized for oseltamivir-sensitive pandemic (H1N1) 2009 and persons hospitalized for the disease but not tested for antiviral susceptibility, England and Scotland, April 27, 2009–April 30, 2010*
Characteristic | No. (%) patients with oseltamivir-sensitive strains, n = 346 | No. (%) patients not tested for antiviral susceptibility, n = 2,471 | χ2 | p value | |||
---|---|---|---|---|---|---|---|
n | With characteristic | n | With characteristic | ||||
Sex | |||||||
M | 346 | 155 (44.8) | 2,471 | 1,176 (47.6) | 0.95 | 0.33 | |
F | 346 | 191 (55.2) | 2,471 | 1295 (52.4) | |||
Age group, y | |||||||
0–4 | 346 | 64 (18.5) | 2,471 | 479 (19.4) | |||
5–14 | 346 | 83 (24.0) | 2,471 | 463 (18.7) | 2.72 | 0.099 | |
15–24 | 346 | 59 (17.1) | 2,471 | 406 (16.4) | 0.19 | 0.663 | |
25–44 | 346 | 74 (21.4) | 2,471 | 611 (24.7) | 0.29 | 0.590 | |
45–64 | 346 | 56 (16.2) | 2,471 | 391 (15.8) | 0.13 | 0.718 | |
>65 | 346 | 10 (2.9) | 2,471 | 121 (4.9) | 1.86 | 0.173 | |
Any predisposing disease | 278 | 164 (59.0) | 1,985 | 1,315 (66.2) | 5.67 | 0.017 | |
Respiratory | 284 | 94 (33.1) | 2,198 | 652 (29.7) | 1.41 | 0.235 | |
Cardiac | 273 | 12 (4.4) | 2,170 | 107 (4.9) | 0.15 | 0.699 | |
Renal | 275 | 11 (4.0) | 2,173 | 69 (3.2) | 0.52 | 0.469 | |
Liver | 272 | 3 (1.1) | 2,170 | 23 (1.1) | 0.004 | 1.000† | |
Neurologic | 269 | 15 (5.6) | 2,181 | 135 (6.2) | 0.16 | 0.692 | |
Immunosuppression | 275 | 19 (6.9) | 1,980 | 237 (12.0) | 6.14 | 0.013 | |
Diabetes | 276 | 6 (2.2) | 2,173 | 104 (4.8) | 3.89 | 0.048 | |
Pregnancy | 301 | 19 (6.3) | 2,216 | 171 (7.7) | 0.75 | 0.387 | |
Other chronic disease | 258 | 32 (12.4) | 1,836 | 262 (14.3) | 0.65 | 0.419 | |
Complications | 346 | 76 (22.0) | 2,471 | 392 (15.9) | 8.15 | 0.004 | |
Respiratory | 346 | 67(19.4) | 2,471 | 374 (15.1) | 4.11 | 0.043 | |
Cardiac | 346 | 2 (0.6) | 2,471 | 0 | 14.29 | 0.015† | |
Renal | 346 | 8 (2.3) | 2,471 | 33 (1.3) | 2.02 | 0.155 | |
Liver | 346 | 1 (0.3) | 2,471 | 0 | 7.14 | 0.123† | |
Neurologic | 346 | 5 (1.4) | 2,471 | 2 (0.08) | 22.78 | <0.001† | |
Otitis | 346 | 0 | 2,471 | 1 (0.04) | 0.14 | 1.000† | |
Other | 346 | 12 (3.5) | 2,471 | 22 (0.9) | 16.91 | <0.001 | |
ICU admission | 205 | 59 (28.8) | 1,542 | 258 (16.7) | 17.69 | <0.001 | |
Death | 322 | 18 (5.6) | 2,253 | 78 (3.5) | 3.55 | 0.059
*n indicates no. patients with information available for that category. ICU, intensive care unit. |
*n indicates no. patients with information available for that category. ICU, intensive care unit.
†By Fisher exact test.