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Volume 17, Number 11—November 2011

CME ACTIVITY

Close Similarity between Sequences of Hepatitis E Virus Recovered from Humans and Swine, France, 2008−2009

Earning Medscape CME Credit

To obtain credit, you should first read the journal article. After reading the article, you should be able to answer the following, related, multiple-choice questions. To complete the questions (with a minimum 70% passing score) and earn continuing medical education (CME) credit, please go to www.medscape.org/journal/eid. Credit cannot be obtained for tests completed on paper, although you may use the worksheet below to keep a record of your answers. You must be a registered user on Medscape.org. If you are not registered on Medscape.org, please click on the New Users: Free Registration link on the left hand side of the website to register. Only one answer is correct for each question. Once you successfully answer all post-test questions you will be able to view and/or print your certificate. For questions regarding the content of this activity, contact the accredited provider, CME@medscape.net. For technical assistance, contact CME@webmd.net. American Medical Association’s Physician’s Recognition Award (AMA PRA) credits are accepted in the US as evidence of participation in CME activities. For further information on this award, please refer to http://www.ama-assn.org/ama/pub/category/2922.html. The AMA has determined that physicians not licensed in the US who participate in this CME activity are eligible for AMA PRA Category 1 Credits™. Through agreements that the AMA has made with agencies in some countries, AMA PRA credit may be acceptable as evidence of participation in CME activities. If you are not licensed in the US, please complete the questions online, print the certificate and present it to your national medical association for review.

Article Title: Close Similarity between Sequences of Hepatitis E Virus Recovered from Humans and Swine, France, 2008−2009


Medscape CME Questions

1. Based on the French study by Dr. Bouquet and colleagues, which of the following statements about epidemiologic features of autochthonous hepatitis E virus (HEV) infections is most likely correct?

A. Most cases are in women

B. Most cases are in adolescents and young adults

C. Genotypes 1 and 2 are the cause of sporadic cases in industrialized countries

D. Waterborne outbreaks of HEV in developing countries may differ epidemiologically and genetically from cases reported in industrialized countries

2. Based on the study by Dr. Bouquet and colleagues, which of the following statements about the genetic identity of HEV strains found in humans and swine during an 18-month period in France is most likely correct?

A. About half of sequences belonged to genotype 3

B. Similarity of about 75% was found between HEV sequences of human and swine origins

C. Subtype 3c was the largest cluster

D. Both human and swine populations had the same proportions of subtypes 3f, 3c, and 3e

3. You are asked to consult with a public health department in southern France regarding a recent increase in autochthonous HEV cases. Based on the study by Dr. Bouquet and colleagues, which of the following statements is most likely to appear in your report?

A. Spread of swine HEV infection within a herd occurs primarily by respiratory droplet transmission

B. The highest risk to humans eating pork products is associated with eating pork chops

C. Environmental factors are a more likely source of exposure than ingestion of pork products

D. A surveillance and control plan, either at the level of pig production or at the level of food processing, is recommended

Activity Evaluation

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2. The material was organized clearly for learning to occur.

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3. The content learned from this activity will impact my practice.

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4. The activity was presented objectively and free of commercial bias.

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