Volume 17, Number 12—December 2011

Research

Candidate Cell Substrates, Vaccine Production, and Transmissible Spongiform Encephalopathies

Pedro Piccardo , Larisa Cervenakova, Irina Vasilyeva, Oksana Yakovleva, Igor Bacik, Juraj Cervenak, Carroll McKenzie, Lubica Kurillova, Luisa Gregori, Kitty Pomeroy, and David M. Asher

Author affiliations: University of Edinburgh, Easter Bush, UK, (P. Piccardo); Food and Drug Administration, Kensington, Maryland, USA (P. Piccardo, I. Bacik, J. Cervenak, L. Kurillova, L. Gregori, K. Pomeroy, D.M. Asher); Holland Laboratory American Red Cross, Rockville, Maryland, USA (L. Cervenakova, I. Vasilyeva, O. Yakovleva, C. McKenzie)

Main Article

Figure 1

Figure 1. Histopathologic analysis of transgenic mouse expressing bovine prion protein (PrP) gene inoculated with bovine spongiform encephalopathy agent. Spongiform degeneration in the thalamus (A), adjacent section showing PrP immunopositivity (B). Panel A was stained with hematoxylin and eosin, panel B was immunostained with PrP antibody 6D11. Scale bars = 100 μm.

Main Article

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