Volume 18, Number 10—October 2012
Research
WU and KI Polyomaviruses in Respiratory Samples from Allogeneic Hematopoietic Cell Transplant Recipients
Jane Kuypers1
, Angela P. Campbell1, Katherine A. Guthrie, Nancy L. Wright, Janet A. Englund, Lawrence Corey, and Michael Boeckh
, Angela P. Campbell1, Katherine A. Guthrie, Nancy L. Wright, Janet A. Englund, Lawrence Corey, and Michael BoeckhTable 2
Characteristics of 222 HCT recipients tested for KIPyV or WUPyV*
| Characteristic |
No. (%) recipients
|
||
|---|---|---|---|
| All, n = 222 | Infected with either virus, n = 62 | Not infected, n = 160 | |
| Age, y | |||
|
<20 |
23 (10) | 18 (29) | 5 (3) |
|
20–39 |
37 (17) | 14 (23) | 23 (14) |
|
40–59 |
99 (45) | 17 (27) | 82 (51) |
|
>60 |
63 (28) | 13 (21) | 50 (31) |
| Sex | |||
|
F |
87 (39) | 23 (37) | 64 (40) |
|
M |
135 (61) | 39 (63) | 96 (60) |
| Underlying disease risk† | |||
|
Standard |
142 (64) | 40 (65) | 102 (64) |
|
High |
80 (36) | 22 (35) | 58 (36) |
| Stem cell source | |||
|
Bone marrow |
28 (13) | 12 (19) | 16 (10) |
|
Peripheral blood |
179 (81) | 47 (76) | 132 (83) |
|
Cord blood |
15 (7) | 3 (5) | 12 (8) |
| CMV serostatus | |||
|
D+/R+ |
56 (25) | 17 (27) | 39 (24) |
|
D+/R– |
81 (36) | 22 (35) | 59 (37) |
|
D–/R+ |
16 (7) | 4 (6) | 12 (8) |
|
D–/R– |
69 (31) | 19 (31) | 50 (31) |
| Donor match | |||
|
Related–matched |
77 (35) | 23 (37) | 54 (34) |
|
Related–mismatched |
9 (4) | 6 (10) | 3 (2) |
|
Unrelated–cord blood |
15 (7) | 3 (5) | 12 (8) |
|
Unrelated–matched |
97 (44) | 24 (39) | 73 (46) |
|
Unrelated–mismatched |
24 (11) | 6 (10) | 18 (11) |
| Conditioning regimen | |||
|
Myeloablative |
128 (58) | 41 (66) | 87 (54) |
|
Nonmyeloablative |
94 (42) | 21 (34) | 73 (46) |
| Acute graft-versus-host disease | |||
|
Grade 0 or 1 |
78 (35) | 30 (48) | 48 (30) |
|
Grade 2–4 |
144 (65) | 32 (52) | 112 (70) |
1These authors contributed equally to this article.
