Characterization of Full Genome of Rat Hepatitis E Virus Strain from Vietnam
Tian-Cheng Li , Yasushi Ami, Yuriko Suzaki, Shumpei P. Yasuda, Kumiko Yoshimatsu, Jiro Arikawa, Naokazu Takeda, and Wakita Takaji
Author affiliations: Author affiliations: National Institute of Infectious Diseases, Tokyo, Japan (T.-C. Li, Y. Ami, Y. Suzaki, W. Takaji); Graduate School of Medicine, Hokkaido University, Sapporo, Japan (S.P. Yasuda, K. Yoshimatsu, J. Arikawa); Osaka University, Osaka, Japan (N. Takeda)
Figure. . Phylogenetic relationships among genotypes 1–4, wild boar, rabbit, avian (chicken), and rat hepatitis E virus (HEV) isolates. The nucleic acid sequence alignment was performed by using ClustalX 1.81 (www.clustal.org). The genetic distance was calculated by the Kimura 2-parameter method. A phylogenetic tree with 1,000 bootstrap replicates was generated by the neighbor-joining method, based on the entire genome (A) and open reading frame 3 (B) of the genotypes 1–4, wild boar, rabbit, avian (chicken), and rat HEV isolates. Scale bar indicates nucleotide substitutions per site. Boldface indicates isolates used in this study.
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