Volume 22, Number 9—September 2016
Research
Staphylococcus aureus Regulatory RNAs as Potential Biomarkers for Bloodstream Infections
Valérie Bordeau, Anne Cady, Matthieu Revest, Octavie Rostan, Mohamed Sassi, Pierre Tattevin, Pierre-Yves Donnio, and Brice Felden
Table 1
Clinical characteristics of 42 patients with Staphylococcus aureus bloodstream infections admitted to Rennes University Hospital, Rennes, France*
| Characteristic | Sepsis, n = 25 | Septic shock, n = 17 | p value |
|---|---|---|---|
| Male sex, % | 84 | 84 | 1.00 |
| Age, y | 62.7 (15–97) | 68.1 (33–84) | 0.30 |
| Nosocomial bacteremia | 80 | 41.1 | 0.02 |
| MRSA | 32 | 5.8 | 0.06 |
| Diabetes mellitus | 16 | 29.4 | 0.45 |
| Alcohol abuse | 12 | 35.3 | 0.12 |
| Charlson Comorbidity Index | 1.4 (0–5) | 2.1 (0–5) | 0.06 |
| Endovascular device | 52 | 29.4 | 0.21 |
| SAPS II | 43.2 (14–61) | 60.9 (38–126) | 0.01 |
| Delayed antibiotherapy | 4.6 (0–42) | 3.1 (0–10) | 0.42 |
| Infective endocarditis | 12 | 17.6 | 0.70 |
| C-reactive protein | 186.4 (32–427) | 250.5 (67–445) | 0.17 |
| Polynuclear neutrophils | 14,588 (4,700–33,000) | 14,977 (4,230–26,000) | 0.84 |
| Mortality rate | 8 | 41.2 | 0.01 |
*Values are % or no. (range). MRSA, methicillin-resistant S. aureus; SAPS II, Simplified Acute Physiology Score.
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