Volume 6, Number 2—April 2000
Research
Serologic Response to Culture Filtrate Antigens of Mycobacterium ulcerans during Buruli Ulcer Disease
Karen M. Dobos*†, Ellen A. Spotts*†, Barbara J. Marston*, C. Robert Horsburgh*, and C. Harold King*
Table 2
Serologic and skin test responses of Buruli ulcer patients and healthy controls from the same villages
| Clinical presentation | Total Burulin (+)a | AB to MUCFb (+)c |
|---|---|---|
| Total BU patients (n = 39) | 28 (71.8) | 26 (66.7) |
| (%) | ||
| Healed (n = 16) | 15 (93.8) | 11 (68.8) |
| (%) | ||
| Ulcerative (n = 17) | 11 (64.7) | 11 (64.7) |
| (%) | ||
| Early ulcerative (n = 6) | 2 (33.4) | 4 (66.7) |
| (%) | ||
| No scar or ulcer (n = 21) | 3 (14.3) | 7 (33.3) |
| (%) |
aTotal Burulin (+) numbers and (%) are derived from columns one and two of Table 1 added together without regard to PPD status, and thus represent the highest possible number (percentage) of Burulin (+) BU patients.
bMUCF = Mycobacterium ulcerans culture filtrate.
cDenotes all BU patients and controls with any antibodies detected by Western blot analysis against MUCF.
