Volume 6, Number 2—April 2000
Research
Serologic Response to Culture Filtrate Antigens of Mycobacterium ulcerans during Buruli Ulcer Disease
Karen M. Dobos*†, Ellen A. Spotts*†, Barbara J. Marston*, C. Robert Horsburgh*, and C. Harold King*
Table 3
Antibody responses to specific Mycobacterium ulcerans culture filtrate proteins in all Buruli ulcer patients and controls
| Clinical Presentation | 5 kDa (%) | 36/38 kDa (%) | 70 kDa (%) | All Three (%) | Any (%)a |
|---|---|---|---|---|---|
| Total BU patients (n= 61) (%) | 14 (22.9) | 31 (50.8) | 37 (60.7) | 8 (13.1) | 43 (70.5) |
| Healed (n = 29) | 8 (27.6) | 15 (51.7) | 17 (58.6) | 7 (24.1) | 20 (69.0) |
| Ulcerative (n = 22) | 6 (27.3) | 10 (45.5) | 14 (63.6) | 2 (9.1) | 16 (72.7) |
| Early ulcerative (n=10) (%) | 0 (0.0) | 6 (60.0) | 6 (60.0) | 0 (0.0) | 7 (70.0) |
| No scar or ulcer (n= 27) (%) | 7 (25.9) | 4 (14.8) | 3 (11.1) | 1 (3.7) | 10 (37.0) |
| U.S. TB patients (n= 13) (%) | 3 (23.1) | 3 (23.1) | 0 (0.0) | 0 (0.0) | 4 (30.8) |
aDenotes total number (percentage) of persons within the population with an antibody response to any one, or a mixture of, the three specified MUCF proteins. MUCF = Mycobacterium ulcerans culture filtrate
