Volume 19, Number 7—July 2013
Mutation in Spike Protein Cleavage Site and Pathogenesis of Feline Coronavirus
|Time||Cat 234||Cat 304|
|t = 1||NHTHTRRSRR↓SAPVAV||NHTHTRRSRR↓SAPVAV|
|t = 2||NHTHTRRSLR↓SAPVAV||NHTHTRRARR↓SAPVAV|
*Underlines indicate nucleotide substitution. FCoV, feline coronavirus; S1/S2, cleavage site of spike protein; t = 1, both cats disease-free; ↓ , cleavage site; t = 2, cat 234 feline infectious peritonitis–positive, cat 304 disease-free.
1These authors contributed equally to this article.