Use of Staged Molecular Analysis to Determine Causes of Unexplained Central Nervous System Infections
Chien-Chin Hsu , Rafal Tokarz, Thomas Briese, Hung-Chin Tsai, Phenix-Lan Quan, and W. Ian Lipkin
Author affiliations: Columbia University, New York, New York, USA (C.-C. Hsu, R. Tokarz, T. Briese, P.-L. Quan, W.I. Lipkin); Southern Taiwan University of Science and Technology, Tainan, Taiwan (C.-C. Hsu); Chi-Mei Medical Center, Tainan (C.-C. Hsu); National Yang-Ming University Kaohsiung, Taiwan (H.-C. Tsai); Kaohsiung Veterans General Hospital, Kaohsiung (H.-C. Tsai)
Figure. . Molecular approaches used to investigate central nervous system infections of unknown cause. Routine study of CSF comprised chemistry, direct microbial examinations, antigen tests, and bacterial and viral cultures. CSF, cerebrospinal fluid; +, positive; –, negative.
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