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Volume 17, Number 8—August 2011

CME ACTIVITY

Deaths Associated with Human Adenovirus-14p1 Infections, Europe, 2009–2010

Earning CME Credit

To obtain credit, you should first read the journal article. After reading the article, you should be able to answer the following, related, multiple-choice questions. To complete the questions (with a minimum 70% passing score) and earn continuing medical education (CME) credit, please go to www.medscape.org/journal/eid. Credit cannot be obtained for tests completed on paper, although you may use the worksheet below to keep a record of your answers. You must be a registered user on Medscape.org. If you are not registered on Medscape.org, please click on the New Users: Free Registration link on the left hand side of the website to register. Only one answer is correct for each question. Once you successfully answer all post-test questions you will be able to view and/or print your certificate. For questions regarding the content of this activity, contact the accredited provider, CME@medscape.net. For technical assistance, contact CME@webmd.net. American Medical Association’s Physician’s Recognition Award (AMA PRA) credits are accepted in the US as evidence of participation in CME activities. For further information on this award, please refer to http://www.ama-assn.org/ama/pub/category/2922.html. The AMA has determined that physicians not licensed in the US who participate in this CME activity are eligible for AMA PRA Category 1 Credits™. Through agreements that the AMA has made with agencies in some countries, AMA PRA credit may be acceptable as evidence of participation in CME activities. If you are not licensed in the US, please complete the questions online, print the certificate and present it to your national medical association for review.

Article Title: Deaths Associated with Human Adenovirus-14p1 Infections, Europe, 2009–2010

CME Questions

1. Based on the above case series by Dr. Carr and colleagues, which of the following statements about demographic, genetic, and transmission-related factors associated with human adenovirus-14p1 (HAdV-14p1) infections recently detected in Ireland is most likely correct?

A. These HAdV-14p1 variants are phylogenetically different from those previously detected in the United States

B. Most of the patients were young women

C. Geographic clustering was observed

D. Efficient transmission of HAdV-14p1 appears to require close physical contact

2. You are a public health official asked to consult with local healthcare facilities in a European region where HAdV-14p1 infections have been detected. Based on the above study, which of the following statements about anticipated clinical characteristics and complications associated with HAdV-14p1 infections is most likely to appear in your report?

A. Initial presentation is usually with gastrointestinal symptoms

B. A very small proportion of patients are likely to have significant comorbidity

C. A little less than half of patients are likely to have an unremarkable full recovery

D. No death has been reported in an immunocompetent individual

3. As the public health official described in question 2, which of the following recommendations would you be most likely to make in your report, based on the clinical and public health implications of the case series described above?

A. Surveillance for HAdV-14p1 should remain the same

B. Healthcare workers should be advised that HAdV-14p1 infection is significantly more severe than that of other HAdV serotypes

C. HAdV-positive specimens should be retrospectively investigated for HAdV-14p1, particularly from untyped viruses from patients who had severe or fatal disease without established etiology

D. HAdV-14p1 should not be included in the differential diagnosis of community-acquired pneumonia

Activity Evaluation

1. The activity supported the learning objectives.

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2. The material was organized clearly for learning to occur.

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3. The content learned from this activity will impact my practice.

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4. The activity was presented objectively and free of commercial bias.

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