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Volume 12, Number 9—September 2006
Research

Lymph Node Biopsy Specimens and Diagnosis of Cat-scratch Disease

Jean-Marc Rolain*, Hubert Lepidi*, Michel Zanaret†, Jean-Michel Triglia‡, Gérard Michel§, Pascal-Alexandre Thomas¶, Michèle Texereau#, Andreas Stein***, Anette Romaru††, François Eb‡‡, and Didier Raoult*Comments to Author 
Author affiliations: *Université de la Méditerranée, Marseille, France; †Fédération Oto-Rhingo-Laryngologie, Marseille, France; ‡Hôpital Timone Enfant, Marseille, France; §Hôpital d'Enfants de la Timone, Marseille, France; ¶Hôpital Sainte-Marguerite, Marseille, France; #Fédération de Médecine, Niort, France; **Hôpital de la Conception, Marseille, France; ††Laboratoire de Biologie, Niort, France; ‡‡Centre Hospitalier Universitaire, Amiens, France

Main Article

Table 3

Relevant studies of causes of lymphadenopathy, 1983–2004*

Variable Doberneck (28) Roberts (25) Anthony (29) Freidig (27) Ridder (1) Chau (36) This study
Years 1972–1982 1978–1983 1983 1978–1986 1997–2001 1996–2001 2001–2005
No. patients 169 163 228 419 454 423 786
Mean age, y (range) 34.6 (1–78} (1–90) (0–>60) 46.7 (2–89) 34.9 (2–90) 40 (14–90) 32.0 (1–94)
Infectious diseases (%) 8/79 (10.1) 76 11 (4.8) 66 (15.8) 156 (34.4) 75 (17.7) 391 (49.7)
CSD (%) 0 0 3 0 61 (13.4) 3 245 (31.2)
Mycobacteria (%) 5/79 (6.3) 27 (16.6) 6 (2.6) 24 (5.7) 5 (1.1) 12 (2.8) 54 (6.9)
Staphylococci or streptococci (%) 3/79 41 NA 2 13 2 49
Malignant process (%) 119 (70.4) 51 (31.2%) 60 (26.3) 113 (27.0) 52 (11.5) 95 (17.3) 47 (26%)†
Undiagnosed (%) 42 (24.9) 28 (17.2) 68 (29.8) 113 (27.0) 171 (37.7) 168 (39.7) 350 (44.6)

*CSD, cat-scratch disease.
†Only 181 samples could be tested by histopathologic analysis.

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