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Volume 20, Number 2—February 2014
Research

Lymphocytic Choriomeningitis Virus in Employees and Mice at Multipremises Feeder-Rodent Operation, United States, 2012

Barbara KnustComments to Author , Ute Ströher, Laura Edison, César G. Albariño, Jodi Lovejoy, Emilian Armeanu, Jennifer House, Denise Cory, Clayton Horton, Kathy L. Fowler, Jessica Austin, John Poe, Kraig E. Humbaugh, Lisa Guerrero, Shelley Campbell, Aridth Gibbons, Zachary Reed, Deborah Cannon, Craig Manning, Brett Petersen, Douglas Metcalf, Bret Marsh, Stuart T. Nichol, and Pierre E. Rollin
Author affiliations: Centers for Disease Control and Prevention, Atlanta, Georgia, USA (B. Knust, U. Ströher, L. Edison, C.G. Albarino, L. Guerrero, S. Campbell, A. Gibbons, Z. Reed, D. Cannon, C. Manning, B. Petersen, S.T. Nichol, P.E. Rollin); Georgia Department of Public Health, Atlanta (L. Edison); Indiana Board of Animal Health, Indianapolis, Indiana, USA (J. Lovejoy, D. Metcalf, B. Marsh); Deaconess Hospital, Evansville, Indiana, USA (E. Armeanu); Indiana State Department of Health, Indianapolis (J. House); Vanderburgh County Health Department, Evansville (D. Cory); Green River District Health Department, Owensboro, Kentucky, USA (C. Horton, J. Austin); Kentucky Department for Public Health, Frankfort, Kentucky, USA (K.L. Fowler, J. Poe, K.E. Humbaugh)

Main Article

Table 2

Demographic and clinical features of laboratory-confirmed illness in 5 facility A employees who sought health care after exposure to LCMV-infected mice, Indiana, USA, 2012*

Patient no. Age, y/sex Time employed Onset date Symptoms Clinical findings†
1 27/F 2 y Apr 20 Fever, muscle ache, nausea, vomiting, abdominal pain, diarrhea, malaise, headache Lymphocytic CSF, leukocytosis (13.8), elevated protein in CSF, appendicitis, UTI
2 34/M 1.5 y Apr 11 Fever, nausea, vomiting, malaise, headache, stiff neck Lymphocytic CSF (1,311/µL), elevated protein in CSF
3 28/F 1.5 y Apr 7 Fever, muscle ache, nausea, vomiting, cough, joint pain, photophobia, headache, diarrhea UTI; no blood or CSF collected during medical evaluation
4 48/M 5 d Apr 27 Fever, muscle ache, nausea, vomiting, abdominal pain, cough, headache, diarrhea Lymphocytic CSF, elevated protein in CSF, mild anemia (34.9%), CT normal
5 38/M 2 mo May 14 Fever, muscle ache, nausea, vomiting, joint pain, headache, diarrhea Lymphocytic CSF (320/µL), elevated protein in CSF (77), leukocytosis (15.1), anemia (Hgb 11.5), CT normal

*LCMV, lymphocytic choriomeningitis virus; CSF, cerebrospinal fluid; UTI, urinary tract infection; CT, computed tomographic scan; Hgb, hemoglobin.
†Lymphocytic CSF is defined as >5 lymphocytes/μL; leukocytosis is >11,000 erythrocytes/μL; and elevated protein in CSF is >60 mg/dL.

Main Article

Page created: January 17, 2014
Page updated: January 17, 2014
Page reviewed: January 17, 2014
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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