Volume 10, Number 5—May 2004
Research
Enzyme-Linked Immunosorbent Assay and Serologic Responses to Pneumocystis jiroveci
Kieran R. Daly*
, Judy Koch*, Linda Levin*, and Peter D. Walzer*
, Judy Koch*, Linda Levin*, and Peter D. Walzer*
Table 3
Adjusted odds ratios (95% CI) measuring the associations between Western blot reactivity and participant status (blood donor versus PCP-positive, PCP-negative, HIV) among 189 study participantsa,b
| ELISA | Midpoint | Blood donor: PCP+ (95% CI) | Blood donor: PCP– (95% CI) | Blood donor: HIV (95% CI) |
|---|---|---|---|---|
| 1 |
2.7 |
3.2 (1.6 to 6.7) |
2.2 (1.4 to 3.5) |
2.7 (1.7 to 4.3) |
| 2 |
16 |
5.9 (2.5 to 14.3) |
3.2 (2.0 to 5.3) |
4.3 (2.6 to 7.4) |
| 3 | 35 | 10.0 (2.9 to 33.3) | 9.1 (4.4 to 20.0) | 9.4 (4.6 to 19.3) |
aCI, confidence interval; ELISA, enzyme-linked immunosorbent assay; PCP, Pneumocystis pneumonia.
bOdds ratios measuring the association between Western blot reactivity and participant status were calculated at the midpoints of ELISA measurements over all antigens. Based on 95% confidence intervals, blood donors had significantly increased odds of Western blot reactivity compared to each patient group (p < 0.05) for each ELISA.
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