Volume 13, Number 2—February 2007
Dispatch
Characteristics of Staphylococcus aureus Infections, Chicago Pediatric Hospital
Preeti Jaggi*, Suzanne M. Paule†, Lance R. Peterson†, and Tina Q. Tan*
Table 1
Comparison of clinical characteristics between pediatric patients with invasive CA-MRSA and CA-MSSA*
| Characteristic | Invasive CA-MRSA, n (%) | Invasive CA-MSSA, n (%) | p value |
|---|---|---|---|
| Race | |||
| Black | 16/18 (88) | 3/10 (30) | .01 |
| Caucasian | 0 | 2/10 (20) | .01 |
| Hispanic | 1/18 (6) | 5/10 (50) | .01 |
| Other | 0 | 0 | .01 |
| Unknown | 1/18 (6) | 1/10 (10) | .01 |
| Days of discordant therapy (CA-MRSA) | |||
| Mean ± SD (range) | 2.22 ± 1.76 (0–6) | N/A | |
| Days febrile, mean ± SD (range) | 7.0 ± 4 (0–17) | 5.20 ± 10.0 (0–32) | .03 |
| Days in hospital, mean ± SD (range) | 14.2 ± 7.6 (4–28) | 13.8 ± 16.8 (4–60) | NS |
| Diagnosis† | |||
| Osteomyelitis, acute | 3/18 (38) | 1/10 (10) | NS |
| Ostyeomyelitis, chronic | 2/18 (11) | 4/10 (40) | NS |
| Bacteremia | 5/18 (28) | 2/10 (20) | NS |
| Endocarditis | 0/18 (0) | 2/10 (20) | NS |
| Pyomyositis | 2/18 (11) | 0/10 (0) | NS |
| Liver abscess | 1/18 (6) | 0/10 (0) | NS |
| Pneumonia + empyema | 6/18 (33) | 1/10 (10) | NS |
| Septic joint | 1/18 (6) | 2/10 (20) | NS |
| Fasciitis | 1/18 (6) | 0/10 (0) | NS |
| Toxic-shock syndrome | 1/18 (6) | 0/10 (0) | NS |
| Other‡ | 3/18 (38) | 0/10 (0) | NS |
| Patients with >1 disease manifestation (%) | 7/18 (39) | 1/10 (10) | NS |
| Days of illness before hospitalization, mean ± SD (range) | 6.9 ± 11.8 (1–45) | 10.9 d ± 15 (2–45) | NS |
| Days of positive cultures, mean ± SD (range) | 6.94 ± 9.9 (1–45) | 4.4 ± 2.98 (1–11) | NS |
| Initial leukocyte count‡ (thousand/μL), mean ± SD (range) | 14.8 ± 13.07 (2.4–57.0) | 9.95 ± 4.45 (3.3–17.0) | NS |
*CA-MRSA, community-associated methicillin-resistant Staphylococcus aureus; MSSA, methicillin-sensitive S. aureus; NS, not significant; SD, standard deviation. Among patients with invasive CA-MRSA infection, 1 died.
†Bonferroni correction for multiple comparisons was applied for comparisons of diagnosis.
‡Other diseases included extensive perineal abscess with fistula, subgaleal hematoma, and a subscapular abscess and prostatitis in the same patient. §One initial leukocyte count was unavailable in each patient group.
Page created: June 29, 2010
Page updated: June 29, 2010
Page reviewed: June 29, 2010
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