Volume 14, Number 8—August 2008
Dispatch
Cluster of Falciparum Malaria Cases in UK Airport
Alison J. Rodger*†
, Graham S. Cooke‡§, Rosalynn Ord¶, Colin J. Sutherland¶, and Geoffrey Pasvol*§
, Graham S. Cooke‡§, Rosalynn Ord¶, Colin J. Sutherland¶, and Geoffrey Pasvol*§
Table
Clinical data for 6 US travelers with falciparum malaria returning from East Africa, 2005*
| Patient no. | Malaria severity (4) | Temp, °C | BP, mm Hg | Parasitemia, % | HGB† | Platelets‡ | Creatinine§ | Bilirubin¶ | ALT# | Base excess** |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Severe | 38.2 | 97/52 | 3.5 | 9.3 | 33 | 89 | 71 | 103 | –2.4 |
| 2 | Severe | 40.1 | 132/73 | 3.5 | 16.0 | 38 | 108 | 40 | 101 | 3.1 |
| 3 | Mild | 38.0 | 110/75 | 1.0 | 13.3 | 48 | 70 | 20 | 34 | ND |
| 4 | Severe | 36.4 | 99/63 | 3.5 | 16.5 | 193 | 111 | 22 | 34 | –2.3 |
| 5 | Severe | 39.4 | 105/72 | 1.5 | 16.8 | 121 | 103 | 20 | 38 | -0.8 |
| 6 | Severe | 37.8 | 79/53 | 1.0 | 13.1 | 54 | 102 | 9 | 41 | –4.8 |
*Date of symptom onset for each patient was 2005 Jul 20. Temp, body temperature; BP, blood pressure; HGB, hemoglobin; ALT, alanine aminotransferase; ND, not done.
†Reference range 11–15 g/dL.
‡Reference range 120–308 × 109/L.
§Reference range <100 μm/L. To convert to mg/dL, divide by 88.4.
¶Reference range <19 μm/L. To convert to mg/dL, divide by 17.1.
#Reference range 19–50 U/L.
**In mmol/L. To convert to mEq/L, divide by 1.0.
References
- Thwing J, Skarbinski J, Newman RD, Barber AM, Mali S, Roberts JM, Malaria surveillance—United States, 2005.MMWR Surveill Summ. 2007;56:23–40.PubMedGoogle Scholar
- Health Protection Agency. Malaria is a continuing danger to UK travellers. 2007 [cited 2007 July 1]. Available from http://www.hpa.org.uk/webw/HPAweb&HPAwebStandard/HPAweb_C/1195733731170?p=1171991026241
- Sutherland CJ, Alloueche A, McRobert A, Ord A, Leggat J, Snounou G, Genetic complexity of Plasmodium falciparum gametocytes isolated from the peripheral blood of treated Gambian children.Am J Trop Med Hyg. 2002;66:700–5.PubMedGoogle Scholar
- Hamer DH, Connor BA. Travel health knowledge, attitudes and practices among United States travellers.J Travel Med. 2004;11:23–6.PubMedGoogle Scholar
- Sutherland CJ, Haustein T, Gadalla N, Armstrong M, Doherty JF, Chiodini PL. Chloroquine-resistant Plasmodium falciparum infections among UK travellers returning with malaria after chloroquine prophylaxis.J Antimicrob Chemother. 2007;59:1197–9. DOIPubMedGoogle Scholar
- Davis TM, Supanaranond W, Pukrittayakamee S, Silamut K, White NJ. Evidence for continued two-brood replication of Plasmodium falciparum in vivo during quinine treatment.Acta Trop. 2003;89:41–5. DOIPubMedGoogle Scholar
- Cattamanchi A, Kyabayinze D, Hubbard A, Rosenthal PJ, Dorsey G. Distinguishing recrudescence from reinfection in a longitudinal antimalarial drug efficacy study: comparison of results based on genotyping msp-1, msp-2, and glurp.Am J Trop Med Hyg. 2003;68:133–9.PubMedGoogle Scholar
- Kamau L, Vulule JM. Status of insecticide susceptibility in Anopheles arabiensis from Mwea rice irrigation scheme, Central Kenya.Malar J. 2006;5:46. DOIPubMedGoogle Scholar
Page created: July 12, 2010
Page updated: July 12, 2010
Page reviewed: July 12, 2010
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
Content Credential