Volume 15, Number 4—April 2009
THEME ISSUE
The Amazon Region
Dispatches
Seroprevalence of Kaposi Sarcoma–associated Herpesvirus and Other Serologic Markers in the Brazilian Amazon
Maria C. Nascimento
, Laura M. Sumita, Vanda U. Souza, Helen A. Weiss, Juliane Oliveira, Melissa Mascheretti, Mariana Quiroga, Rodrigo A.R. Vela, Nuno R. Faria, Claudio S. Pannuti, and Philippe Mayaud
, Laura M. Sumita, Vanda U. Souza, Helen A. Weiss, Juliane Oliveira, Melissa Mascheretti, Mariana Quiroga, Rodrigo A.R. Vela, Nuno R. Faria, Claudio S. Pannuti, and Philippe Mayaud
Table 2
Multivariable analysis of risk factors for KSHV infection among 3 populations in the Brazilian Amazon*
| Variables | aOR (95% CI) |
||
|---|---|---|---|
| Mapuera Amerindians, n = 339 | Mapuera non-Amerindians, n = 181 | Manaus blood donors, n = 1,133 | |
| Sex | |||
| Male | 1 | 1 | 1 |
| Female | 1.2 (0.7–2.2) | 1.0 (0.5–2.1) | 1.3 (1.0–1.7) |
| p value |
0.5 |
0.9 |
0.08 |
| Age group, y | |||
| 0–9 | 0.1 (0.05–0.4) | 0.1 (0.04–0.3) | |
| 10–17 | 0.2 (0.07–0.4) | 0.3 (0.1–0.7) | |
| 18–34 | 0.5 (0.2–1.2) | 0.4 (0.1–0.9) | 0.9 (0.7–1.3) |
| >35 | 1 | 1 | 1 |
| p value |
<0.001 |
<0.001 |
0.6 |
| HSV-2 | |||
| Negative | 1 | 1 | 1 |
| Positive | 0.3 (0.1–0.9) | 2.7 (1.2–6.5) | 1.3 (1.0–1.6) |
| p value | 0.03 | 0.02 | 0.09 |
*Seroreactivity by any serologic assay (whole virus ELISA, IFA-LANA, or IFA-lytic) in multivariable analysis. KSHV, Kaposi sarcoma–associated herpesvirus; IFA-LANA, immunofluorescence assay that detected latent-associated nuclear antigens; IFA-lytic, IFA that detected lytic-associated nuclear antigens; aOR, age- and sex-adjusted odds ratio; CI, confidence interval; HSV-2, herpes simplex virus type-2.
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