Volume 15, Number 8—August 2009
Dispatch
Predictors of Death after Severe Streptococcus pyogenes Infection
Theresa L. Lamagni
, Shona Neal, Catherine Keshishian, David Powell, Nicola Potz, Richard G. Pebody, Robert C. George, Georgia Duckworth, Jaana Vuopio-Varkila, and Androulla Efstratiou
, Shona Neal, Catherine Keshishian, David Powell, Nicola Potz, Richard G. Pebody, Robert C. George, Georgia Duckworth, Jaana Vuopio-Varkila, and Androulla Efstratiou
Table
Conditions selected as cause of death within 7 days after diagnosis of severe Streptococcus pyogenes infection, England and Wales, 2003–2004
| Condition classification (International Classification of Diseases, 10th Revision, code), N = 557* | Underlying cause, no. (%) | All mentions,† no. (%) |
|---|---|---|
| Infectious and parasitic diseases (A00–B99) | 67 (12) | 303 (54) |
| Neoplasms (C00–D48) | 52 (9) | 80 (14) |
| Diseases of the blood and blood forming organs and certain disorders involving the immune mechanism (D50–D89) | 0 (0) | 9 (2) |
| Endocrine system (E00–E90) | 12 (2) | 50 (9) |
| Mental and behavioral disorders (F00–F99) | 19 (3) | 32 (6) |
| Diseases of the nervous system (G00–G99) | 7 (1) | 12 (2) |
| Diseases of the eye and adnexa (H00–H59) | 4 (1) | 5 (1) |
| Diseases of the ear and mastoid process (H60–H95) | 2 (<1) | 2 (<1) |
| Diseases of the circulatory system (I00–I99) | 108 (19) | 297 (53) |
| Diseases of the respiratory system (J00–J99) | 99 (18) | 223 (40) |
| Diseases of the digestive system (K00–K93) | 32 (6) | 66 (12) |
| Diseases of the skin and subcutaneous tissue (L00–L99) | 67 (12) | 102 (18) |
| Diseases of the musculoskeletal system and connective tissue (M00–M99) | 39 (7) | 69 (12) |
| Diseases of the genitourinary system (N00–N99) | 17 (3) | 65 (12) |
| Complications of pregnancy, childbirth, and the puerperium (O00–O99) | 1 (<1) | 1 (<1) |
| Certain conditions originating in the perinatal period (P00–P96) | 1 (<1) | 3 (1) |
| Congenital abnormalities (Q00–Q99) | 2 (<1) | 7 (1) |
| Symptoms, signs, and abnormal clinical and laboratory findings not elsewhere classified (R00–R99) | 7 (1) | 49 (9) |
| Injury, poisoning, and certain other consequences of external causes (S00–T98) | 0 (0) | 49 (9) |
| External causes of mortality (V01–Y98) | 21 (4) | 61 (11) |
*Percentages based on 557 deaths (cause of death was not available for 2 patients).
†Conditions noted on the death certificate as the underlying or contributory cause of death.
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