Figure 2. Average cost effectiveness of vaccinating a person against Lyme disease with changes in the cost of vaccination, probabilities of identifying and treating early Lyme disease, and probabilities of contracting Lyme disease. A negative value indicates that vaccinating a person will result in a net cost to society, while a positive value indicates a net savings to society. The results shown are the means from Monte Carlo simulations (see Table 1 and text for further details). Vaccine assumed 85% effective (Table 1).