Skip directly to page options Skip directly to A-Z link
Volume 7, Number 6—December 2001
Dispatch

Vancomycin-Intermediate Staphylococcus aureus in a Home Health-Care Patient

Jeffrey C. Hageman*Comments to Author , David A. Pegues†, Carrie Jepson‡, Rose Lee Bell‡, Mary Guinan§, Kevin W. Ward†, Martin D. Cohen†, Janet A. Hindler†, Fred C. Tenover*, Sigrid K. McAllister*, Molly E. Kellum*, and Scott K. Fridkin*
Author affiliations: *Centers for Disease Control and Prevention, Atlanta, Georgia, USA;; †University of California Los Angeles Medical Center, Los Angeles, California, USA;; ‡Clark County Health District, Las Vegas, Nevada, USA;; §Nevada State Health Division, Carson City, Nevada, USA

Main Article

Figure 2

Pulsed-field gel electrophoresis profiles of SmaI digested DNA. NCTC, National Collection of Type Cultures 8325 control. Lane 1, vancomycin-intermediate Staphylococcus aureus (VISA) isolate from Japan, otherwise designated Mu50; lane 2, VISA isolate from Michigan (7); lane 3, VISA isolate from New Jersey (7); Lane 4, VISA isolate from New York (1); lane 5, VISA isolate from Illinois (3); lane 7, patient's oxacillin-resistant VISA; lane 8, patient's oxacillin-susceptible VISA; lane 9 patient's ox

Figure 2. Pulsed-field gel electrophoresis profiles of SmaI digested DNA. NCTC, National Collection of Type Cultures 8325 control. Lane 1, vancomycin-intermediate Staphylococcus aureus (VISA) isolate from Japan, otherwise designated Mu50; lane 2, VISA isolate from Michigan (7); lane 3, VISA isolate from New Jersey (7); Lane 4, VISA isolate from New York (1); lane 5, VISA isolate from Illinois (3); lane 7, patient's oxacillin-resistant VISA; lane 8, patient's oxacillin-susceptible VISA; lane 9 patient's oxacillin-resistant S. aureus (ORSA, vancomycin MIC = 2 µg/mL) from anterior nares; lanes 10 and 11, isolates of ORSA (vancomycin MIC=2 µg/mL) from the health-care worker's anterior nares.

Download

Main Article

References
  1. Rotun  SS, McMath  V, Schoonmaker  DJ, Maupin  PS, Tenover  FC, Hill  BC, with reduced susceptibility to vancomycin isolated from a patient with fatal bacteremia. Emerg Infect Dis. 1999;5:147–9. DOIPubMedGoogle Scholar
  2. Centers for Disease Control and Prevention. Reduced susceptibility of Staphylococcus aureus to vancomycin--Japan, 1996. MMWR Morb Mortal Wkly Rep. 1997;46:624–6.PubMedGoogle Scholar
  3. Centers for Disease Control and Prevention. Staphylococcus aureus . MMWR Morb Mortal Wkly Rep. 2000;48:1165–7.PubMedGoogle Scholar
  4. Vannuffel  P, Gigi  J, Ezzedine  H, Vanderman  B, Delmee  M, Wauters  G, Specific detection of methicillin-resistant Staphylococcus aureus species by multiplex PCR. J Clin Microbiol. 1995;33:2864–7.PubMedGoogle Scholar
  5. Centers for Disease Control and Prevention. Interim guidelines for prevention and control of staphylococcal infection associated with reduced susceptibility to vancomycin. MMWR Morb Mortal Wkly Rep. 1997;46:626–35.PubMedGoogle Scholar
  6. Kloos  WE, Bannerman  TL. Staphylococcus and micrococcus. In: Murray PR, editor. Manual of clinical microbiology. 7th ed. Washington: American Society for Microbiology Press; 1999. p. 264-82.
  7. National Committee for Clinical Laboratory Standards. Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically. 5th ed. Approved standard M7-A5. Wayne (PA): The Committee; 2001.
  8. Tenover  FC, Arbeit  RD, Goering  RV, Mickelsen  PA, Murray  BE, Persing  DH, Interpreting chromosomal DNA restriction patterns produced by pulsed-field gel electrophoresis: criteria for bacterial strain typing. J Clin Microbiol. 1995;33:2233–9.PubMedGoogle Scholar
  9. Smith  TL, Pearson  ML, Wilcox  KR, Cruz  C, Lancaster  MV, Robinson-Dunn  B, Emergence of vancomycin resistance in Staphylococcus aureus. N Engl J Med. 1999;340:493–501. DOIPubMedGoogle Scholar
  10. Fridkin  SK. Vancomycin-intermediate and -resistant Staphylococcus aureus: what the infectious disease specialist needs to know. Clin Infect Dis. 2001;32:108–15. DOIPubMedGoogle Scholar

Main Article

Page created: December 09, 2010
Page updated: December 09, 2010
Page reviewed: December 09, 2010
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
file_external