Skip directly to site content Skip directly to page options Skip directly to A-Z link Skip directly to A-Z link Skip directly to A-Z link
Volume 9, Number 12—December 2003
Dispatch

Mycobacterium tuberculosis Beijing Genotype and Risk for Treatment Failure and Relapse, Vietnam

Nguyen Thi Ngoc Lan*, Hoang Thi Kim Lien*, Le B. Tung*, Martien W. Borgdorff†‡, Kristin Kremer§, and Dick van Soolingen§Comments to Author 
Author affiliations: *Pham Ngoc Thach Tuberculosis and Lung Diseases Centre, Ho Chi Minh City, Vietnam; †Royal Netherlands Tuberculosis Association, The Hague, the Netherlands; ‡University of Amsterdam, the Netherlands; §National Institute of Public Health and the Environment, Bilthoven, the Netherlands

Main Article

Table

Characteristics at enrollment of case-patients who experienced treatment failure and relapse and of controls who did not experience treatment failure, relapse, or diea

Characteristic Failure
 Relapse
 All case-patients
 Controls
 Crude
 Adjustedb
 Adjustedc
OR 95% CI OR 95% CI OR 95% CI
Sex
Male
 28
 36
 64
 104
 1
1
Female
 12
 3
 15
 39
 0.63
 0.32 to 1.22
0.55
 0.22 to 1.38
Age group (y)
15–34
 15
 9
 24
 60
 1
1
35–54
 22
 25
 47
 72
 1.63
 0.90 to 3.0
2.0
 0.90 to 4.6
>55
 3
 5
 8
 11
 1.82
 0.65 to 5.1
2.4
 0.60 to 9.9
Genotype
Beijing
 32
 29
 61
 75
 2.8
 1.48 to 5.15
 2.5
 1.2 to 5.2
 3.2
 1.4 to 7.1
Other
 8
 10
 18
 61
 1
1
1
Unknown
7
Resistance pattern
Fully susc.
 4
 13
 17
 101
 1
1
1
S only
 3
 9
 12
 21
 3.4
 1.41 to 8.2
 4.0
 1.6 to 9.9
 3.9
 1.54 to 9.9
H only
 3
 4
 7
 10
 4.2
 1.39 to 12
 4.7
 1.5 to 15
 5.0
 1.54 to 16
Other
 30d
 13e
 43
 11
 23
 10.0 to 54
 23
 9.7 to 55
 26
 10.3 to 64
TOTAL 40 39 79 143

a OR, odds ratio; CI, confidence interval; susc., susceptible.
bAdjusted for genotype and resistance pattern.
cAdjusted for age, sex, genotype, and resistance pattern.
dOf these 30, 12 had resistance to H and S, 1 to H, S, and E, 10 to H, R, and S, and 7 to H, R, S, E.
eOf these 13, 11 had resistance to H and S, and 2 to H, S, and E.

Main Article

Page created: February 08, 2011
Page updated: February 08, 2011
Page reviewed: February 08, 2011
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
file_external