Volume 9, Number 3—March 2003
Dispatch
Persistence of Virus-Reactive Serum Immunoglobulin M Antibody in Confirmed West Nile Virus Encephalitis Cases
John T. Roehrig*
, Denis Nash†, Beth Maldin†, Anne Labowitz†, Denise A. Martin*, Robert S. Lanciotti*, and Grant L. Campbell*
, Denis Nash†, Beth Maldin†, Anne Labowitz†, Denise A. Martin*, Robert S. Lanciotti*, and Grant L. Campbell*
Table 2
Percent of persons with IgM-positive serology by months after onseta
| Number WNV IgM positive/total (%) |
|||||
|---|---|---|---|---|---|
| Acute
(n=27) |
3 months
(n=15) |
6 months
(n=23) |
9 months
(n=23) |
12 months
(n=18) |
|
| Age |
|||||
| <65 yrs |
9/9 (100) |
6/6 (100) |
6/9 (67) |
4/8 (50) |
0/5 (0) |
| +65 yrs |
18/18 (100) |
9/9 (100) |
9/14 (64) |
5/15 (33) |
2/13 (15) |
| Sex |
|||||
| Male |
13/13 (100) |
8/8 (100) |
8/11 (73) |
3/10 (30) |
1/9 (11) |
| Female |
14/14 (100) |
7/7 (100) |
7/12 (58) |
6/13 (46) |
1/9 (11) |
| Clinical syndrome |
|||||
| Encephalitis |
16/16 (100) |
8/8 (100) |
8/13 (62) |
5/13 (39) |
2/11 (18) |
| Meningitis |
11/11 (100) |
7/7 (100) |
7/10 (70) |
4/10 (40) |
0/7 (0) |
| Baseline IgMb |
|||||
| <Median P/N |
14/14 (100) |
6/6 (100) |
6/11 (55) |
3/12 (25) |
0/10 (0) |
| >median P/N | 13/13 (100) | 9/9 (100) | 9/12 (75) | 6/11 (55) | 2/8 (25) |
aWNV, West Nile virus; Ig, immunoglobulin; P/N, positive-to-negative; P/N ratio > 3.0.
bMedian P/N = 11.4.
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Page updated: December 07, 2010
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