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Volume 9, Number 3—March 2003
Dispatch

Persistence of Virus-Reactive Serum Immunoglobulin M Antibody in Confirmed West Nile Virus Encephalitis Cases

John T. Roehrig*Comments to Author , Denis Nash†, Beth Maldin†, Anne Labowitz†, Denise A. Martin*, Robert S. Lanciotti*, and Grant L. Campbell*
Author affiliations: *Centers for Disease Control and Prevention, Fort Collins, Colorado, USA; †New York City Department of Health, New York, New York, USA

Main Article

Table 2

Percent of persons with IgM-positive serology by months after onseta


Number WNV IgM positive/total (%)
Acute
(n=27)
3 months
(n=15)
6 months
(n=23)
9 months
(n=23)
12 months
(n=18)
Age
<65 yrs
9/9 (100)
6/6 (100)
6/9 (67)
4/8 (50)
0/5 (0)
+65 yrs
18/18 (100)
9/9 (100)
9/14 (64)
5/15 (33)
2/13 (15)
Sex
Male
13/13 (100)
8/8 (100)
8/11 (73)
3/10 (30)
1/9 (11)
Female
14/14 (100)
7/7 (100)
7/12 (58)
6/13 (46)
1/9 (11)
Clinical syndrome
Encephalitis
16/16 (100)
8/8 (100)
8/13 (62)
5/13 (39)
2/11 (18)
Meningitis
11/11 (100)
7/7 (100)
7/10 (70)
4/10 (40)
0/7 (0)
Baseline IgMb
<Median P/N
14/14 (100)
6/6 (100)
6/11 (55)
3/12 (25)
0/10 (0)
>median P/N 13/13 (100) 9/9 (100) 9/12 (75) 6/11 (55) 2/8 (25)

aWNV, West Nile virus; Ig, immunoglobulin; P/N, positive-to-negative; P/N ratio > 3.0.
bMedian P/N = 11.4.

Main Article

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Page updated: December 07, 2010
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